Inhibition of lymphoproliferation by dipyridamole

Dipyridamole (DP, Persantin) was examined for its effects on the proliferation of mitogen-stimulated murine splenocytes and L1210 leukemia cells. In keeping with its reported activity as an inhibitor of nucleoside transport, DP inhibited incorporation by lymphoid cells of labeled thymidine and uridi...

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Veröffentlicht in:	Biochemical pharmacology 1982-04, Vol.31 (7), p.1381-1386
Hauptverfasser:	Farmer, Jeffrey L., Prager, Morton D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport - drug effects Cell Division - drug effects Cell Survival - drug effects Cells, Cultured Dipyridamole - pharmacology In Vitro Techniques Leukemia L1210 - pathology Lymphocytes - cytology Lymphocytes - drug effects Lymphocytes - metabolism Macromolecular Substances Male Mice Mice, Inbred A Spleen - cytology
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