Tissue concentrations of free amino acids in term human placentas
Five human term placentas were analyzed for total free amino acid concentrations. Calculation of tissue fluid distribution via 14C-inulin space enabled an estimation of placental intracellular amino acid concentrations based upon cord and maternal plasma concentrations. Maximum and minimum estimates...
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| Veröffentlicht in: | American journal of obstetrics and gynecology 1978-08, Vol.131 (8), p.881-887 |
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| container_title | American journal of obstetrics and gynecology |
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| creator | Philipps, Anthony F. Holzman, Ian R. Teng, Cecilia Battaglia, Frederick C. |
| description | Five human term placentas were analyzed for total free amino acid concentrations. Calculation of tissue fluid distribution via 14C-inulin space enabled an estimation of placental intracellular amino acid concentrations based upon cord and maternal plasma concentrations. Maximum and minimum estimates for amino acid concentration in intracellular water are given. Data are compared to concentrations in organs of various species. Taurine was present in the highest concentration (3.529±1.120 μmoles per gram wet weight). Glutamic and aspartic acids, alanine, glycine, and glutamine were all present in concentrations greater than 0.5μmoles per gram wet weight. |
| doi_str_mv | 10.1016/S0002-9378(16)33136-2 |
| format | Article |
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Calculation of tissue fluid distribution via 14C-inulin space enabled an estimation of placental intracellular amino acid concentrations based upon cord and maternal plasma concentrations. Maximum and minimum estimates for amino acid concentration in intracellular water are given. Data are compared to concentrations in organs of various species. Taurine was present in the highest concentration (3.529±1.120 μmoles per gram wet weight). Glutamic and aspartic acids, alanine, glycine, and glutamine were all present in concentrations greater than 0.5μmoles per gram wet weight.</description><identifier>ISSN: 0002-9378</identifier><identifier>EISSN: 1097-6868</identifier><identifier>DOI: 10.1016/S0002-9378(16)33136-2</identifier><identifier>PMID: 686088</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Amino Acids - analysis ; Amino Acids - blood ; Amino Acids - metabolism ; Female ; Humans ; Placenta - analysis ; Placenta - metabolism ; Pregnancy ; Taurine - analysis ; Taurine - blood ; Taurine - metabolism ; Tissue Distribution</subject><ispartof>American journal of obstetrics and gynecology, 1978-08, Vol.131 (8), p.881-887</ispartof><rights>1978 The C. V. 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Calculation of tissue fluid distribution via 14C-inulin space enabled an estimation of placental intracellular amino acid concentrations based upon cord and maternal plasma concentrations. Maximum and minimum estimates for amino acid concentration in intracellular water are given. Data are compared to concentrations in organs of various species. Taurine was present in the highest concentration (3.529±1.120 μmoles per gram wet weight). Glutamic and aspartic acids, alanine, glycine, and glutamine were all present in concentrations greater than 0.5μmoles per gram wet weight.</description><subject>Amino Acids - analysis</subject><subject>Amino Acids - blood</subject><subject>Amino Acids - metabolism</subject><subject>Female</subject><subject>Humans</subject><subject>Placenta - analysis</subject><subject>Placenta - metabolism</subject><subject>Pregnancy</subject><subject>Taurine - analysis</subject><subject>Taurine - blood</subject><subject>Taurine - metabolism</subject><subject>Tissue Distribution</subject><issn>0002-9378</issn><issn>1097-6868</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1LxDAQxYP4ta7-Bwo5iR6qk6abtCdZFr9gwYN7D2kyxUjbrEkr-N_b2mWvnobHe2-G-RFyxeCOARP37wCQJgWX-Q0Tt5wzLpL0gMwYFDIRucgPyWwfOSVnMX6OMi3SE3I8-JDnM7LcuBh7pMa3Btsu6M75NlJf0SogUt241lNtnI3UtbTD0NCPvtEt3dZ6LOh4To4qXUe82M052Tw9blYvyfrt-XW1XCcmY6xLci4YCmAopZBWyrLkJVZQ2TLjhS1AQMYBFpXIs1RkYBcFMpEyYUxmAQSfk-tp7Tb4rx5jpxoXDda1btH3UcmMAZfZYggupqAJPsaAldoG1-jwoxioEZz6A6dGKmpQf-BUOvQudwf6skG7b02kBvthsnH48dthUNE4HKBZF9B0ynr3z4Ffpwh7qg</recordid><startdate>19780815</startdate><enddate>19780815</enddate><creator>Philipps, Anthony F.</creator><creator>Holzman, Ian R.</creator><creator>Teng, Cecilia</creator><creator>Battaglia, Frederick C.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19780815</creationdate><title>Tissue concentrations of free amino acids in term human placentas</title><author>Philipps, Anthony F. ; Holzman, Ian R. ; Teng, Cecilia ; Battaglia, Frederick C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-8361e601e7767d77bb3bef0fdb439d906043005f6842640d59e16216cc4d0063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1978</creationdate><topic>Amino Acids - analysis</topic><topic>Amino Acids - blood</topic><topic>Amino Acids - metabolism</topic><topic>Female</topic><topic>Humans</topic><topic>Placenta - analysis</topic><topic>Placenta - metabolism</topic><topic>Pregnancy</topic><topic>Taurine - analysis</topic><topic>Taurine - blood</topic><topic>Taurine - metabolism</topic><topic>Tissue Distribution</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Philipps, Anthony F.</creatorcontrib><creatorcontrib>Holzman, Ian R.</creatorcontrib><creatorcontrib>Teng, Cecilia</creatorcontrib><creatorcontrib>Battaglia, Frederick C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of obstetrics and gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Philipps, Anthony F.</au><au>Holzman, Ian R.</au><au>Teng, Cecilia</au><au>Battaglia, Frederick C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tissue concentrations of free amino acids in term human placentas</atitle><jtitle>American journal of obstetrics and gynecology</jtitle><addtitle>Am J Obstet Gynecol</addtitle><date>1978-08-15</date><risdate>1978</risdate><volume>131</volume><issue>8</issue><spage>881</spage><epage>887</epage><pages>881-887</pages><issn>0002-9378</issn><eissn>1097-6868</eissn><abstract>Five human term placentas were analyzed for total free amino acid concentrations. Calculation of tissue fluid distribution via 14C-inulin space enabled an estimation of placental intracellular amino acid concentrations based upon cord and maternal plasma concentrations. Maximum and minimum estimates for amino acid concentration in intracellular water are given. Data are compared to concentrations in organs of various species. Taurine was present in the highest concentration (3.529±1.120 μmoles per gram wet weight). Glutamic and aspartic acids, alanine, glycine, and glutamine were all present in concentrations greater than 0.5μmoles per gram wet weight.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>686088</pmid><doi>10.1016/S0002-9378(16)33136-2</doi><tpages>7</tpages></addata></record> |
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| identifier | ISSN: 0002-9378 |
| ispartof | American journal of obstetrics and gynecology, 1978-08, Vol.131 (8), p.881-887 |
| issn | 0002-9378 1097-6868 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Amino Acids - analysis Amino Acids - blood Amino Acids - metabolism Female Humans Placenta - analysis Placenta - metabolism Pregnancy Taurine - analysis Taurine - blood Taurine - metabolism Tissue Distribution |
| title | Tissue concentrations of free amino acids in term human placentas |
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