Angiotensin II mediated acth release in rat pituitary cell culture

Anterior pituitaries from normal rats were enzymatically dispersed and placed into monolayer cell culture in order to determine if and how angiotensin II (Ang II) mediates the in vitro release of ACTH and other pituitary hormones. Ang II stimulated ACTH secretion in a time dependent fashion. This re...

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Veröffentlicht in:	Life sciences (1973) 1982-04, Vol.30 (15), p.1281-1286
Hauptverfasser:	Sobel, Douglas, Vagnucci, Anthony
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenocorticotropic Hormone - metabolism angiotensin Angiotensin II - physiology Animals Cells, Cultured corticotropin Cycloheximide - pharmacology Dose-Response Relationship, Drug Female In Vitro Techniques pituitary (anterior) Pituitary Gland - metabolism Protein Biosynthesis Rats Rats, Inbred Strains Time Factors
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