Effect of a new 5α-reductase inhibitor on size, histologic characteristics, and androgen concentrations of the canine prostate

Mature male beagles were used in studies designed to determine the effect of the steroidal 5α‐reductase inhibitor 17β‐N,N‐diethylcarbamoyl‐4‐aza‐4‐methyl‐5α‐androstan‐3‐one (4‐MA) on size, histology, and androgen concentration of the prostate. Subcutaneous administration of 3 or 15 mg/kg/day for 43...

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