Effect of THD-341, a new hypocholesterolemic agent, on experimental atherosclerosis in rabbits

The influence of THD-341, N-(2,6-dimethylphenyl)-Δ 8-dihydroabietamide, upon the formation and regression of atherosclerosis and on serum and liver lipid levels has been studied. When rabbits were fed a 1% cholesterol diet for 7 weeks, THD-341 added at a dietary level of 0.01% during the last 4 week...

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Veröffentlicht in:	Atherosclerosis 1978-06, Vol.30 (2), p.109-121
Hauptverfasser:	Enomoto, H., Yoshikuni, Y., Saito, K., Ozaki, T., Ohata, K., Zschocke, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticholesteremic Agents - therapeutic use Aorta Aorta - pathology Arteriosclerosis - drug therapy Arteriosclerosis - pathology Arteriosclerosis - prevention & control Atherosclerosis Cholesterol Coronary artery Diterpenes - therapeutic use Hypocholesterolemic drug Lipids - blood Liver cholesterol Male N-(2,6-Dimethylphenyl)-Δ 8-dihydroabietamide (THD-341) Rabbit Rabbits Serum cholesterol
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