Ontogeny of Gastric Acid Secretion in the Rat: Evidence for Multiple Response Systems

Gastric acid secretion has been thought to depend on histamine stimulation of the parietal cell. However, in the 2-week-old rat neither exogenous histamine nor the H-2 receptor agonist impromidine stimulates acid secretion, whereas pentagastrin and the cholinergic agent bethanechol are potent stimul...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1982-07, Vol.217 (4554), p.75-77
1. Verfasser:	Ackerman, Sigurd H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Analysis of variance Animals Bethanechol Compounds - pharmacology Cholinergic agents Food intake Gastric juice Gastric Juice - drug effects Gastric Juice - metabolism Gastric Mucosa - growth & development Guanidines - pharmacology Histamine - pharmacology Histamine antagonists Histamines Imidazoles - pharmacology Impromidine Neurons Ontogeny Pentagastrin - pharmacology Purines Rats Rats, Inbred Strains Receptors Receptors, Histamine H2 - drug effects Secretion Secretions Stomach
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