Characterization of cells transformed by Ad5/Ad12 hybrid early region I plasmids

Early region I (EI) of the human adenoviruses consists of two transcriptional units, EIa and EIb. We have constructed plasmids containing hybrid EI regions from the nononcogenic adenovirus type 5 (Ad5) and the highly oncogenic Ad12. Each plasmid essentially contains the EIa region of one serotype an...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1982-07, Vol.120 (2), p.422-432
Hauptverfasser:	Bernards, Rene, Houweling, Ada, Schrier, Peter I., Bos, Johannes L., Van Der Eb, Alex J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviruses, Human Animals Base Sequence Cell Line Cell Transformation, Viral Cloning, Molecular DNA, Recombinant DNA, Viral - genetics Gene Expression Regulation Genes, Viral Mice Mice, Nude Neoplasms, Experimental - etiology Plasmids Rats
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