Immunocompetency in anorexia nervosa
Twenty-two consecutively admitted patients diagnosed for anorexia nervosa were evaluated for cellular immune functioning by means of an anergy panel to test delayed hypersensitivity. The panel included Candida, streptokinase-streptodornase, and mumps antigen administered by a standard protocol. A st...
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| Veröffentlicht in: | The American journal of clinical nutrition 1982-05, Vol.35 (5), p.968-972 |
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| container_title | The American journal of clinical nutrition |
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| creator | Pertschuk, M J Crosby, L O Barot, L Mullen, J L |
| description | Twenty-two consecutively admitted patients diagnosed for anorexia nervosa were evaluated for cellular immune functioning by means of an anergy panel to test delayed hypersensitivity. The panel included Candida, streptokinase-streptodornase, and mumps antigen administered by a standard protocol. A standard nutritional profile including current weight, usual weight, total protein, albumin, total iron-binding capacity, white blood cell count, total lymphocyte count, triceps skinfold, and arm muscle circumference was concurrently compiled on these subjects. Six of 22 patients studied were anergic. Visceral protein measures were generally within normal limits even in the most depleted patients. Malnutrition as measured by severity of weight loss and triceps skinfolds was significantly related to anergy, whereas visceral protein indicators (serum albumin, total iron binding capacity, transferrin) were not correlated with anergy. Anergy appeared to be related more strongly to anthropometric indices of malnutrition than to visceral protein values. Cellular immunity was generally preserved until weight loss was far advanced. |
| doi_str_mv | 10.1093/ajcn/35.5.968 |
| format | Article |
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Cellular immunity was generally preserved until weight loss was far advanced.</description><identifier>ISSN: 0002-9165</identifier><identifier>EISSN: 1938-3207</identifier><identifier>DOI: 10.1093/ajcn/35.5.968</identifier><identifier>PMID: 7081094</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Anorexia nervosa ; Anorexia Nervosa - complications ; Anorexia Nervosa - immunology ; Anthropometry ; Blood Cell Count ; Body Weight ; Female ; Humans ; Hypersensitivity, Delayed ; immune system ; Immunity, Cellular ; Immunocompetence ; Male ; malnutrition ; Nutrition Disorders - etiology ; Nutrition Disorders - immunology ; nutritional status</subject><ispartof>The American journal of clinical nutrition, 1982-05, Vol.35 (5), p.968-972</ispartof><rights>1982 American Institute of Nutrition.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c425t-771ac410c96a33c3a4f240c16b73c2bedd8d472e88e3eb4781c06b28c8058be63</citedby><cites>FETCH-LOGICAL-c425t-771ac410c96a33c3a4f240c16b73c2bedd8d472e88e3eb4781c06b28c8058be63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27915,27916</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7081094$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pertschuk, M J</creatorcontrib><creatorcontrib>Crosby, L O</creatorcontrib><creatorcontrib>Barot, L</creatorcontrib><creatorcontrib>Mullen, J L</creatorcontrib><title>Immunocompetency in anorexia nervosa</title><title>The American journal of clinical nutrition</title><addtitle>Am J Clin Nutr</addtitle><description>Twenty-two consecutively admitted patients diagnosed for anorexia nervosa were evaluated for cellular immune functioning by means of an anergy panel to test delayed hypersensitivity. The panel included Candida, streptokinase-streptodornase, and mumps antigen administered by a standard protocol. A standard nutritional profile including current weight, usual weight, total protein, albumin, total iron-binding capacity, white blood cell count, total lymphocyte count, triceps skinfold, and arm muscle circumference was concurrently compiled on these subjects. Six of 22 patients studied were anergic. Visceral protein measures were generally within normal limits even in the most depleted patients. Malnutrition as measured by severity of weight loss and triceps skinfolds was significantly related to anergy, whereas visceral protein indicators (serum albumin, total iron binding capacity, transferrin) were not correlated with anergy. Anergy appeared to be related more strongly to anthropometric indices of malnutrition than to visceral protein values. Cellular immunity was generally preserved until weight loss was far advanced.</description><subject>Adult</subject><subject>Anorexia nervosa</subject><subject>Anorexia Nervosa - complications</subject><subject>Anorexia Nervosa - immunology</subject><subject>Anthropometry</subject><subject>Blood Cell Count</subject><subject>Body Weight</subject><subject>Female</subject><subject>Humans</subject><subject>Hypersensitivity, Delayed</subject><subject>immune system</subject><subject>Immunity, Cellular</subject><subject>Immunocompetence</subject><subject>Male</subject><subject>malnutrition</subject><subject>Nutrition Disorders - etiology</subject><subject>Nutrition Disorders - immunology</subject><subject>nutritional status</subject><issn>0002-9165</issn><issn>1938-3207</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQQIMotVaPXgShB_G2bb6TPUrxo1DwoD2HbHZWUrqbmuyK_fdu2eJNPM3hvZmBh9A1wTOCcza3G9fMmZiJWS71CRqTnOmMUaxO0RhjTLOcSHGOLlLaYEwo13KERgrrfpmP0d2yrrsmuFDvoIXG7ae-mdomRPj2dtpA_ArJXqKzym4TXB3nBK2fHt8XL9nq9Xm5eFhljlPRZkoR6zjBLpeWMccsryjHjshCMUcLKEtdckVBa2BQcKWJw7Kg2mksdAGSTdD9cHcXw2cHqTW1Tw62W9tA6JJRHEtJ5P8iYYIpkYtezAbRxZBShMrsoq9t3BuCzSGfOeQzTBhh-ny9f3s83BU1lL_2sVfPbwZe2WDsR_TJrN80ZUyIA1QDhL7Rl4dokvN9Uyh9BNeaMvg_3v4AnbaFcQ</recordid><startdate>198205</startdate><enddate>198205</enddate><creator>Pertschuk, M J</creator><creator>Crosby, L O</creator><creator>Barot, L</creator><creator>Mullen, J L</creator><general>Elsevier Inc</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>198205</creationdate><title>Immunocompetency in anorexia nervosa</title><author>Pertschuk, M J ; Crosby, L O ; Barot, L ; Mullen, J L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c425t-771ac410c96a33c3a4f240c16b73c2bedd8d472e88e3eb4781c06b28c8058be63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Adult</topic><topic>Anorexia nervosa</topic><topic>Anorexia Nervosa - complications</topic><topic>Anorexia Nervosa - immunology</topic><topic>Anthropometry</topic><topic>Blood Cell Count</topic><topic>Body Weight</topic><topic>Female</topic><topic>Humans</topic><topic>Hypersensitivity, Delayed</topic><topic>immune system</topic><topic>Immunity, Cellular</topic><topic>Immunocompetence</topic><topic>Male</topic><topic>malnutrition</topic><topic>Nutrition Disorders - etiology</topic><topic>Nutrition Disorders - immunology</topic><topic>nutritional status</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pertschuk, M J</creatorcontrib><creatorcontrib>Crosby, L O</creatorcontrib><creatorcontrib>Barot, L</creatorcontrib><creatorcontrib>Mullen, J L</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of clinical nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pertschuk, M J</au><au>Crosby, L O</au><au>Barot, L</au><au>Mullen, J L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Immunocompetency in anorexia nervosa</atitle><jtitle>The American journal of clinical nutrition</jtitle><addtitle>Am J Clin Nutr</addtitle><date>1982-05</date><risdate>1982</risdate><volume>35</volume><issue>5</issue><spage>968</spage><epage>972</epage><pages>968-972</pages><issn>0002-9165</issn><eissn>1938-3207</eissn><abstract>Twenty-two consecutively admitted patients diagnosed for anorexia nervosa were evaluated for cellular immune functioning by means of an anergy panel to test delayed hypersensitivity. The panel included Candida, streptokinase-streptodornase, and mumps antigen administered by a standard protocol. A standard nutritional profile including current weight, usual weight, total protein, albumin, total iron-binding capacity, white blood cell count, total lymphocyte count, triceps skinfold, and arm muscle circumference was concurrently compiled on these subjects. Six of 22 patients studied were anergic. Visceral protein measures were generally within normal limits even in the most depleted patients. Malnutrition as measured by severity of weight loss and triceps skinfolds was significantly related to anergy, whereas visceral protein indicators (serum albumin, total iron binding capacity, transferrin) were not correlated with anergy. Anergy appeared to be related more strongly to anthropometric indices of malnutrition than to visceral protein values. Cellular immunity was generally preserved until weight loss was far advanced.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>7081094</pmid><doi>10.1093/ajcn/35.5.968</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | The American journal of clinical nutrition, 1982-05, Vol.35 (5), p.968-972 |
| issn | 0002-9165 1938-3207 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adult Anorexia nervosa Anorexia Nervosa - complications Anorexia Nervosa - immunology Anthropometry Blood Cell Count Body Weight Female Humans Hypersensitivity, Delayed immune system Immunity, Cellular Immunocompetence Male malnutrition Nutrition Disorders - etiology Nutrition Disorders - immunology nutritional status |
| title | Immunocompetency in anorexia nervosa |
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