Pigment mutations associated with altered circadian rhythms in mice
Mammalian albinism is known to alter neural pathways, reduce retinal pigment, and affect diverse behaviors. Mammalian circadian rhythms have been shown to depend on visual pathways, respond to light intensity and regulate many behaviors. Here we show that mice homozygous for the recessive albino or...
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Veröffentlicht in: | Physiology & behavior 1982-03, Vol.28 (3), p.389-392 |
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creator | Possidente, Bernard Hegmann, Joseph P. Carlson, Linda Elder, Bruce |
description | Mammalian albinism is known to alter neural pathways, reduce retinal pigment, and affect diverse behaviors. Mammalian circadian rhythms have been shown to depend on visual pathways, respond to light intensity and regulate many behaviors. Here we show that mice homozygous for the recessive albino or pinkeye-dilute mutations display shorter circadian rhythms than pigmented controls. We conclude that these pigment loci, or closely linked loci, influence the expression of circadian rhythms in mice. |
doi_str_mv | 10.1016/0031-9384(82)90129-9 |
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Mammalian circadian rhythms have been shown to depend on visual pathways, respond to light intensity and regulate many behaviors. Here we show that mice homozygous for the recessive albino or pinkeye-dilute mutations display shorter circadian rhythms than pigmented controls. We conclude that these pigment loci, or closely linked loci, influence the expression of circadian rhythms in mice.</description><identifier>ISSN: 0031-9384</identifier><identifier>EISSN: 1873-507X</identifier><identifier>DOI: 10.1016/0031-9384(82)90129-9</identifier><identifier>PMID: 7079353</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Albino locus ; Animals ; Circadian Rhythm ; Circadian rhythms ; Female ; Male ; Mice ; Mice, Inbred Strains - genetics ; Mice, Inbred Strains - physiology ; Motor Activity ; Mus musculus ; Mutation ; Pigments, Biological - genetics ; Pinkeye-dilute locus ; Species Specificity ; Wheel running activity</subject><ispartof>Physiology & behavior, 1982-03, Vol.28 (3), p.389-392</ispartof><rights>1982</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-3e5db1245abc38785865138edbfe1005b04c3ac8b0f31dda2fc4f66ec2770a893</citedby><cites>FETCH-LOGICAL-c357t-3e5db1245abc38785865138edbfe1005b04c3ac8b0f31dda2fc4f66ec2770a893</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0031-9384(82)90129-9$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7079353$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Possidente, Bernard</creatorcontrib><creatorcontrib>Hegmann, Joseph P.</creatorcontrib><creatorcontrib>Carlson, Linda</creatorcontrib><creatorcontrib>Elder, Bruce</creatorcontrib><title>Pigment mutations associated with altered circadian rhythms in mice</title><title>Physiology & behavior</title><addtitle>Physiol Behav</addtitle><description>Mammalian albinism is known to alter neural pathways, reduce retinal pigment, and affect diverse behaviors. Mammalian circadian rhythms have been shown to depend on visual pathways, respond to light intensity and regulate many behaviors. Here we show that mice homozygous for the recessive albino or pinkeye-dilute mutations display shorter circadian rhythms than pigmented controls. We conclude that these pigment loci, or closely linked loci, influence the expression of circadian rhythms in mice.</description><subject>Albino locus</subject><subject>Animals</subject><subject>Circadian Rhythm</subject><subject>Circadian rhythms</subject><subject>Female</subject><subject>Male</subject><subject>Mice</subject><subject>Mice, Inbred Strains - genetics</subject><subject>Mice, Inbred Strains - physiology</subject><subject>Motor Activity</subject><subject>Mus musculus</subject><subject>Mutation</subject><subject>Pigments, Biological - genetics</subject><subject>Pinkeye-dilute locus</subject><subject>Species Specificity</subject><subject>Wheel running activity</subject><issn>0031-9384</issn><issn>1873-507X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAQhoMo67r6DxR6Ej1UkyZp0osgi1-woAcFbyFNpm6kH2uSKvvvbd1lj85lGOadd3gfhE4JviKY5NcYU5IWVLILmV0WmGRFWuyhKZGCphyL93003UkO0VEIn3goyugETQQWBeV0iuYv7qOBNiZNH3V0XRsSHUJnnI5gkx8Xl4muI_hhMM4bbZ1uE79cx2UTEtcmjTNwjA4qXQc42fYZeru_e50_povnh6f57SI1lIuYUuC2JBnjujRUCsllzgmVYMsKCMa8xMxQbWSJK0qs1VllWJXnYDIhsJYFnaHzje_Kd189hKgaFwzUtW6h64MSDOdMDLFmiG2ExncheKjUyrtG-7UiWI3s1AhGjWCUzNQfOzX6n239-7IBuzvawhr2N5s9DCG_HXgVjIPWgHUeTFS2c_8_-AV5f34i</recordid><startdate>198203</startdate><enddate>198203</enddate><creator>Possidente, Bernard</creator><creator>Hegmann, Joseph P.</creator><creator>Carlson, Linda</creator><creator>Elder, Bruce</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198203</creationdate><title>Pigment mutations associated with altered circadian rhythms in mice</title><author>Possidente, Bernard ; Hegmann, Joseph P. ; Carlson, Linda ; Elder, Bruce</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-3e5db1245abc38785865138edbfe1005b04c3ac8b0f31dda2fc4f66ec2770a893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Albino locus</topic><topic>Animals</topic><topic>Circadian Rhythm</topic><topic>Circadian rhythms</topic><topic>Female</topic><topic>Male</topic><topic>Mice</topic><topic>Mice, Inbred Strains - genetics</topic><topic>Mice, Inbred Strains - physiology</topic><topic>Motor Activity</topic><topic>Mus musculus</topic><topic>Mutation</topic><topic>Pigments, Biological - genetics</topic><topic>Pinkeye-dilute locus</topic><topic>Species Specificity</topic><topic>Wheel running activity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Possidente, Bernard</creatorcontrib><creatorcontrib>Hegmann, Joseph P.</creatorcontrib><creatorcontrib>Carlson, Linda</creatorcontrib><creatorcontrib>Elder, Bruce</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Physiology & behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Possidente, Bernard</au><au>Hegmann, Joseph P.</au><au>Carlson, Linda</au><au>Elder, Bruce</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pigment mutations associated with altered circadian rhythms in mice</atitle><jtitle>Physiology & behavior</jtitle><addtitle>Physiol Behav</addtitle><date>1982-03</date><risdate>1982</risdate><volume>28</volume><issue>3</issue><spage>389</spage><epage>392</epage><pages>389-392</pages><issn>0031-9384</issn><eissn>1873-507X</eissn><abstract>Mammalian albinism is known to alter neural pathways, reduce retinal pigment, and affect diverse behaviors. Mammalian circadian rhythms have been shown to depend on visual pathways, respond to light intensity and regulate many behaviors. Here we show that mice homozygous for the recessive albino or pinkeye-dilute mutations display shorter circadian rhythms than pigmented controls. We conclude that these pigment loci, or closely linked loci, influence the expression of circadian rhythms in mice.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>7079353</pmid><doi>10.1016/0031-9384(82)90129-9</doi><tpages>4</tpages></addata></record> |
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subjects | Albino locus Animals Circadian Rhythm Circadian rhythms Female Male Mice Mice, Inbred Strains - genetics Mice, Inbred Strains - physiology Motor Activity Mus musculus Mutation Pigments, Biological - genetics Pinkeye-dilute locus Species Specificity Wheel running activity |
title | Pigment mutations associated with altered circadian rhythms in mice |
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