Pigment mutations associated with altered circadian rhythms in mice

Mammalian albinism is known to alter neural pathways, reduce retinal pigment, and affect diverse behaviors. Mammalian circadian rhythms have been shown to depend on visual pathways, respond to light intensity and regulate many behaviors. Here we show that mice homozygous for the recessive albino or...

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Veröffentlicht in:Physiology & behavior 1982-03, Vol.28 (3), p.389-392
Hauptverfasser: Possidente, Bernard, Hegmann, Joseph P., Carlson, Linda, Elder, Bruce
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container_title Physiology & behavior
container_volume 28
creator Possidente, Bernard
Hegmann, Joseph P.
Carlson, Linda
Elder, Bruce
description Mammalian albinism is known to alter neural pathways, reduce retinal pigment, and affect diverse behaviors. Mammalian circadian rhythms have been shown to depend on visual pathways, respond to light intensity and regulate many behaviors. Here we show that mice homozygous for the recessive albino or pinkeye-dilute mutations display shorter circadian rhythms than pigmented controls. We conclude that these pigment loci, or closely linked loci, influence the expression of circadian rhythms in mice.
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source MEDLINE; Elsevier ScienceDirect Journals Complete
subjects Albino locus
Animals
Circadian Rhythm
Circadian rhythms
Female
Male
Mice
Mice, Inbred Strains - genetics
Mice, Inbred Strains - physiology
Motor Activity
Mus musculus
Mutation
Pigments, Biological - genetics
Pinkeye-dilute locus
Species Specificity
Wheel running activity
title Pigment mutations associated with altered circadian rhythms in mice
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