Biological Effects of Nonalkaloid-Containing Fractions of Erythroxylon coca

Water soluble nonalkaloid fractions of Erythroxylon coca were screened in mice for their effects on oxygen utilization and central nervous system (CNS) activity. The fractions were screened in dogs for cardiovascular, blood glucose, and respiratory changes. No CNS effects were demonstrated in mice;...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1982-06, Vol.71 (6), p.677-679
Hauptverfasser:	Harland, Ernest C., Murphy, James C., Elsohly, Hala, Greubel, Deborah, Turner, Carlton E., Watson, E.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Glucose - metabolism Blood Pressure - drug effects CNS activity-effect of nonalkaloid-containing fractions of Erythroxylon coca Coca Dogs effects Erythroxylon coca-biological effects of nonalkaloid-containing fractions Heart Rate - drug effects Hemodynamics - drug effects Male Mice Mice, Inbred ICR Motor Activity - drug effects Nonalkaloids-fractions in Erythroxylon coca Nonalkaloids—fractions in Erythroxylon coca, effects Oxygen Consumption - drug effects Oxygen utilization rate-effects of Erythroxylon coca on oxygen utilization rate Oxygen utilization rate—effects of Erythroxylon coca on oxygen utilization rate, mice, dogs Plant Extracts - pharmacology Plants, Medicinal Respiration - drug effects
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