Serum prealbumin levels in alpha 1-antitrypsin deficiency (PiZ)
The relationship between low serum prealbumin levels and alpha 1-antitrypsin deficiency (PiZ) was investigated. Pi typing was done by acid starch gel electrophoresis followed by crossed antigen-antibody electrophoresis and/or immunofixation. Serum prealbumin levels were determined by radial immunodi...
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| Veröffentlicht in: | Metabolism, clinical and experimental clinical and experimental, 1982-03, Vol.31 (3), p.299-302 |
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| container_title | Metabolism, clinical and experimental |
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| creator | Berninger, Ronald W. Booker, Susan V. Talamo, Richard C. |
| description | The relationship between low serum prealbumin levels and alpha
1-antitrypsin deficiency (PiZ) was investigated. Pi typing was done by acid starch gel electrophoresis followed by crossed antigen-antibody electrophoresis and/or immunofixation. Serum prealbumin levels were determined by radial immunodiffusion. While the serum concentration of prealbumin was low in nine of the fifteen PiZ children, this could be explained by the presence of liver disease in eight of those patients; one patient was asymptomatic. In contrast, only one of the twelve adult PiZ patients exhibited a low prealbumin level, also due to liver disease. We conclude that there is no direct association between PiZ alpha
1-antitrypsin deficiency and low serum prealbumin levels in children or adults. |
| doi_str_mv | 10.1016/0026-0495(82)90069-5 |
| format | Article |
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1-antitrypsin deficiency (PiZ) was investigated. Pi typing was done by acid starch gel electrophoresis followed by crossed antigen-antibody electrophoresis and/or immunofixation. Serum prealbumin levels were determined by radial immunodiffusion. While the serum concentration of prealbumin was low in nine of the fifteen PiZ children, this could be explained by the presence of liver disease in eight of those patients; one patient was asymptomatic. In contrast, only one of the twelve adult PiZ patients exhibited a low prealbumin level, also due to liver disease. We conclude that there is no direct association between PiZ alpha
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1-antitrypsin deficiency (PiZ) was investigated. Pi typing was done by acid starch gel electrophoresis followed by crossed antigen-antibody electrophoresis and/or immunofixation. Serum prealbumin levels were determined by radial immunodiffusion. While the serum concentration of prealbumin was low in nine of the fifteen PiZ children, this could be explained by the presence of liver disease in eight of those patients; one patient was asymptomatic. In contrast, only one of the twelve adult PiZ patients exhibited a low prealbumin level, also due to liver disease. We conclude that there is no direct association between PiZ alpha
1-antitrypsin deficiency and low serum prealbumin levels in children or adults.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>alpha 1-Antitrypsin Deficiency</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Electrophoresis, Starch Gel</subject><subject>Female</subject><subject>Humans</subject><subject>Immunoelectrophoresis</subject><subject>Infant</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Phenotype</subject><subject>Prealbumin - analysis</subject><subject>Serum Albumin - analysis</subject><issn>0026-0495</issn><issn>1532-8600</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE1Lw0AQhhdRaq3-A4WcpD1EZzfZj1wUKX5BQcGevCy72QmuJG3cTQr996a2eJph3peB5yHkksINBSpuAZhIIS_4VLFZASCKlB-RMeUZS5UAOCbj_8opOYvxGwCkVGJERqKQqlBqTO4_MPRN0gY0te0bv0pq3GAdk2EzdftlEpqaVee7sG3jcHNY-dLjqtwm03f_OTsnJ5WpI14c5oQsnx6X85d08fb8On9YpEhBqTQXJROGGqtc6SxKkKaSYEFgwbEsLFJeoRR5xVkmGVBnOSgqnbBgmcyzCbnev23D-qfH2OnGxxLr2qxw3Uctc-B5nsFQvDoUe9ug023wjQlbfQAe8rt9PjDixmPQ8Q8HnQ9Ydtqtvaagd4L1zp7e2dOK6T_Bmme_j_FrJQ</recordid><startdate>198203</startdate><enddate>198203</enddate><creator>Berninger, Ronald W.</creator><creator>Booker, Susan V.</creator><creator>Talamo, Richard C.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>198203</creationdate><title>Serum prealbumin levels in alpha 1-antitrypsin deficiency (PiZ)</title><author>Berninger, Ronald W. ; Booker, Susan V. ; Talamo, Richard C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e1088-46c26a1ab8dcdbe707af70b06e95ec9be15fe764f5237201db50817d6b0b2743</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>alpha 1-Antitrypsin Deficiency</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Electrophoresis, Starch Gel</topic><topic>Female</topic><topic>Humans</topic><topic>Immunoelectrophoresis</topic><topic>Infant</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Phenotype</topic><topic>Prealbumin - analysis</topic><topic>Serum Albumin - analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Berninger, Ronald W.</creatorcontrib><creatorcontrib>Booker, Susan V.</creatorcontrib><creatorcontrib>Talamo, Richard C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Metabolism, clinical and experimental</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Berninger, Ronald W.</au><au>Booker, Susan V.</au><au>Talamo, Richard C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Serum prealbumin levels in alpha 1-antitrypsin deficiency (PiZ)</atitle><jtitle>Metabolism, clinical and experimental</jtitle><addtitle>Metabolism</addtitle><date>1982-03</date><risdate>1982</risdate><volume>31</volume><issue>3</issue><spage>299</spage><epage>302</epage><pages>299-302</pages><issn>0026-0495</issn><eissn>1532-8600</eissn><abstract>The relationship between low serum prealbumin levels and alpha
1-antitrypsin deficiency (PiZ) was investigated. Pi typing was done by acid starch gel electrophoresis followed by crossed antigen-antibody electrophoresis and/or immunofixation. Serum prealbumin levels were determined by radial immunodiffusion. While the serum concentration of prealbumin was low in nine of the fifteen PiZ children, this could be explained by the presence of liver disease in eight of those patients; one patient was asymptomatic. In contrast, only one of the twelve adult PiZ patients exhibited a low prealbumin level, also due to liver disease. We conclude that there is no direct association between PiZ alpha
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| subjects | Adolescent Adult Aged alpha 1-Antitrypsin Deficiency Child Child, Preschool Electrophoresis, Starch Gel Female Humans Immunoelectrophoresis Infant Male Middle Aged Phenotype Prealbumin - analysis Serum Albumin - analysis |
| title | Serum prealbumin levels in alpha 1-antitrypsin deficiency (PiZ) |
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