Effect of Clinical Concentrations of Halothane on Phospholipid-Cholesterol Membrane Fluidity

Wide variation exists among estimates of the concentration of the inhalation anesthetic halothane (2-bromo-2-chloro-1,1,1-trifluoroethane) in the phospholipid-cholesterol bilayer membrane of a nerve cell exposed to clinical anesthetic concentrations. Attempts to adapt octanol/water partition coeffic...

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Veröffentlicht in:	Molecular pharmacology 1978-05, Vol.14 (3), p.463-467
Hauptverfasser:	Mastrangelo, C J, Trudell, J R, Edmunds, H N, Cohen, E N
Format:	Artikel
Sprache:	eng
Schlagworte:	Cholesterol - metabolism Halothane - metabolism Halothane - pharmacology Membranes, Artificial Phospholipids - metabolism Viscosity
Online-Zugang:	Volltext
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