Simultaneous and Specific Determination of Proxyphylline, Theophylline and other Xanthine Derivatives in Serum by High Pressure Liquid Chromatography

A HPLC‐method for rapid, simultaneous and specific determination of proxyphylline, theophylline, glyphylline, theobromine, caffeine and 3‐methylxanthine using 8‐chlorotheophylline as internal standard is presented. Using 20 μl deproteinised serum samples for injection, the detection limits for theop...

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Veröffentlicht in:	Acta pharmacologica et toxicologica 1978-04, Vol.42 (4), p.298-302
Hauptverfasser:	Nielsen‐Kudsk, F., Pedersen, A. Kirstein
Format:	Artikel
Sprache:	eng
Schlagworte:	Caffeine - blood Chromatography, High Pressure Liquid - instrumentation Chromatography, High Pressure Liquid - methods high pressure liquid chromatography Humans Indicators and Reagents Proxyphylline in serum Theobromine - blood Theophylline - blood theophylline in serum Xanthines - blood
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