The dexamethasone suppression test in prepubertal depressed children

The authors evaluated 18 dysphoric children aged 6--12 years by structured clinical assessments and an overnight dexamethasone suppression test (DST) administered on an outpatient basis. Nine children met diagnostic criteria for major depressive disorder, and 8 of the 9 also met the Research Diagnos...

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Veröffentlicht in:The American journal of psychiatry 1982-03, Vol.139 (3), p.321-324
Hauptverfasser: Poznanski, E O, Carroll, B J, Banegas, M C, Cook, S C, Grossman, J A
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container_end_page 324
container_issue 3
container_start_page 321
container_title The American journal of psychiatry
container_volume 139
creator Poznanski, E O
Carroll, B J
Banegas, M C
Cook, S C
Grossman, J A
description The authors evaluated 18 dysphoric children aged 6--12 years by structured clinical assessments and an overnight dexamethasone suppression test (DST) administered on an outpatient basis. Nine children met diagnostic criteria for major depressive disorder, and 8 of the 9 also met the Research Diagnostic Criteria for endogenous depression. Of the 9 depressed children, 5 had abnormal DST results; 8 of the 9 nondepressed children had normal test results. The results suggest that endogenous depression in childhood is not a rare condition and that it is clinically and neuroendocrinologically similar to the adult disorder. The DST may be useful as a diagnostic aid with depressed children.
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source MEDLINE; Psychiatry Legacy Collection Online Journals 1844-1996; Periodicals Index Online
subjects Child
Depressive Disorder - diagnosis
Depressive Disorder - psychology
Dexamethasone
Female
Humans
Hydrocortisone - blood
Male
Pilot Projects
title The dexamethasone suppression test in prepubertal depressed children
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