Responsiveness to estradiol in central nervous system of aging female rats
The age related decline in reproductive capacity in the female rat is examined in terms of physiological and behavioral changes in responsiveness to estradiol evidenced during the second year of life. After 9–12 months of age, regular estrous cycles are replaced by constant estrous, prolonged pseudo...
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| Veröffentlicht in: | Neuroscience and biobehavioral reviews 1982-01, Vol.6 (1), p.39-45 |
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| container_title | Neuroscience and biobehavioral reviews |
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| creator | Dudley, Susan D. |
| description | The age related decline in reproductive capacity in the female rat is examined in terms of physiological and behavioral changes in responsiveness to estradiol evidenced during the second year of life. After 9–12 months of age, regular estrous cycles are replaced by constant estrous, prolonged pseudopregnancy, or anestrous states, with concurrent alterations in endocrine function. Some of the mechanisms implicated in the mediation of these changes are reviewed. Estrogenic influences on estrous behavior and the control of feeding and body weight in aged rats, as well as the effects of parity on aged endocrinological functioning are discussed. |
| doi_str_mv | 10.1016/0149-7634(82)90005-7 |
| format | Article |
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After 9–12 months of age, regular estrous cycles are replaced by constant estrous, prolonged pseudopregnancy, or anestrous states, with concurrent alterations in endocrine function. Some of the mechanisms implicated in the mediation of these changes are reviewed. 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After 9–12 months of age, regular estrous cycles are replaced by constant estrous, prolonged pseudopregnancy, or anestrous states, with concurrent alterations in endocrine function. Some of the mechanisms implicated in the mediation of these changes are reviewed. Estrogenic influences on estrous behavior and the control of feeding and body weight in aged rats, as well as the effects of parity on aged endocrinological functioning are discussed.</description><subject>Aging</subject><subject>Aging rat</subject><subject>Anestrus - drug effects</subject><subject>Animals</subject><subject>Body weight</subject><subject>Body Weight - drug effects</subject><subject>Brain - drug effects</subject><subject>Brain - physiology</subject><subject>Estradiol</subject><subject>Estradiol - pharmacology</subject><subject>Estradiol - physiology</subject><subject>Estradiol receptor</subject><subject>Estrous behavior</subject><subject>Estrus - drug effects</subject><subject>Feeding Behavior - drug effects</subject><subject>Feeding Behavior - physiology</subject><subject>Female</subject><subject>Hypothalamo-Hypophyseal System - drug effects</subject><subject>Hypothalamo-Hypophyseal System - physiology</subject><subject>Hypothalamo-pituitary axis</subject><subject>Ovary - physiology</subject><subject>Parity</subject><subject>Pituitary Gland - drug effects</subject><subject>Pituitary Gland - physiology</subject><subject>Pregnancy</subject><subject>Rats - physiology</subject><subject>Receptors, Estrogen - drug effects</subject><subject>Receptors, Estrogen - physiology</subject><subject>Research Design</subject><subject>Sexual Behavior, Animal - physiology</subject><issn>0149-7634</issn><issn>1873-7528</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kFtLAzEQhYMotV7-gUKeRB9Wc9lskhdBilcKguhzyG5mS2Q3W5NtwX9vaouPPg3DnHNm5kPojJJrSmh1Q2ipC1nx8lKxK00IEYXcQ1OqJC-kYGofTf8kh-gopc-sYYSLCZpIUuYMMUUvb5CWQ0h-DQFSwuOAIY3ROj902AfcQMhdhwPE9bBKOH2nEXo8tNgufFjgFnrbAY52TCfooLVdgtNdPUYfD_fvs6di_vr4PLubFw0XciwqSWquaSnqWgmiq5o6DZWorNbWKWYJMOtawR0nJejWSQJON6zNHkEcV_wYXWxzl3H4WuVrTe9TA11nA-QTjSwJU1SVWVhuhU0cUorQmmX0vY3fhhKzQWg2fMyGj1HM_CI0MtvOd_mrugf3Z9oxy_Pb7Rzyk2sP0aTGQ2jA-QjNaNzg_1_wAxJBgB8</recordid><startdate>19820101</startdate><enddate>19820101</enddate><creator>Dudley, Susan D.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19820101</creationdate><title>Responsiveness to estradiol in central nervous system of aging female rats</title><author>Dudley, Susan D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-670b39145bb85096b1d9e656a99ad82a0e2adf53d304e9fd70ed9c2f39150d383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Aging</topic><topic>Aging rat</topic><topic>Anestrus - drug effects</topic><topic>Animals</topic><topic>Body weight</topic><topic>Body Weight - drug effects</topic><topic>Brain - drug effects</topic><topic>Brain - physiology</topic><topic>Estradiol</topic><topic>Estradiol - pharmacology</topic><topic>Estradiol - physiology</topic><topic>Estradiol receptor</topic><topic>Estrous behavior</topic><topic>Estrus - drug effects</topic><topic>Feeding Behavior - drug effects</topic><topic>Feeding Behavior - physiology</topic><topic>Female</topic><topic>Hypothalamo-Hypophyseal System - drug effects</topic><topic>Hypothalamo-Hypophyseal System - physiology</topic><topic>Hypothalamo-pituitary axis</topic><topic>Ovary - physiology</topic><topic>Parity</topic><topic>Pituitary Gland - drug effects</topic><topic>Pituitary Gland - physiology</topic><topic>Pregnancy</topic><topic>Rats - physiology</topic><topic>Receptors, Estrogen - drug effects</topic><topic>Receptors, Estrogen - physiology</topic><topic>Research Design</topic><topic>Sexual Behavior, Animal - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dudley, Susan D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroscience and biobehavioral reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dudley, Susan D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Responsiveness to estradiol in central nervous system of aging female rats</atitle><jtitle>Neuroscience and biobehavioral reviews</jtitle><addtitle>Neurosci Biobehav Rev</addtitle><date>1982-01-01</date><risdate>1982</risdate><volume>6</volume><issue>1</issue><spage>39</spage><epage>45</epage><pages>39-45</pages><issn>0149-7634</issn><eissn>1873-7528</eissn><abstract>The age related decline in reproductive capacity in the female rat is examined in terms of physiological and behavioral changes in responsiveness to estradiol evidenced during the second year of life. After 9–12 months of age, regular estrous cycles are replaced by constant estrous, prolonged pseudopregnancy, or anestrous states, with concurrent alterations in endocrine function. Some of the mechanisms implicated in the mediation of these changes are reviewed. Estrogenic influences on estrous behavior and the control of feeding and body weight in aged rats, as well as the effects of parity on aged endocrinological functioning are discussed.</abstract><cop>United States</cop><pub>Elsevier Ltd</pub><pmid>7041015</pmid><doi>10.1016/0149-7634(82)90005-7</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0149-7634 |
| ispartof | Neuroscience and biobehavioral reviews, 1982-01, Vol.6 (1), p.39-45 |
| issn | 0149-7634 1873-7528 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aging Aging rat Anestrus - drug effects Animals Body weight Body Weight - drug effects Brain - drug effects Brain - physiology Estradiol Estradiol - pharmacology Estradiol - physiology Estradiol receptor Estrous behavior Estrus - drug effects Feeding Behavior - drug effects Feeding Behavior - physiology Female Hypothalamo-Hypophyseal System - drug effects Hypothalamo-Hypophyseal System - physiology Hypothalamo-pituitary axis Ovary - physiology Parity Pituitary Gland - drug effects Pituitary Gland - physiology Pregnancy Rats - physiology Receptors, Estrogen - drug effects Receptors, Estrogen - physiology Research Design Sexual Behavior, Animal - physiology |
| title | Responsiveness to estradiol in central nervous system of aging female rats |
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