A Platelet-Inhibitor-Drug Trial in Coronary-Artery Bypass Operations: Benefit of Perioperative Dipyridamole and Aspirin Therapy on Early Postoperative Vein-Graft Patency

To prevent occlusion of aortocoronary-artery-bypass grafts, we conducted a prospective, randomized-double-blind trial comparing dipyridamole (instituted two days before operation) plus aspirin (added seven hours after operation) with placebo in 407 patients. Vein-graft angiography was performed in 3...

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Veröffentlicht in:	The New England journal of medicine 1982-07, Vol.307 (2), p.73-78
Hauptverfasser:	Chesebro, J. H, Clements, I. P, Fuster, V, Elveback, L. R, Smith, H. C, Bardsley, W. T, Frye, R. L, Holmes, D. R, Vlietstra, R. E, Pluth, J. R, Wallace, R. B, Puga, F. J, Orszulak, T. A, Piehler, J. M, Schaff, H. V, Danielson, G. K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Angiography Anticoagulants Aspirin Aspirin - therapeutic use Blood platelets Blood Platelets - drug effects Clinical trials Clinical Trials as Topic Coronary artery Coronary Artery Bypass Dipyridamole Dipyridamole - therapeutic use Double-Blind Method Double-blind studies Female Heart surgery Humans Male Medical imaging Middle Aged Occlusion Postoperative Care Postoperative Complications - prevention & control Prospective Studies Random Allocation Thromboembolism Thrombosis - prevention & control Urine Veins & arteries
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