Oxalic acid and the hyperoxaluric syndromes
Because calcium oxalate renal stones are the most common type of renal calculus found in this country, a discussion of oxalic acid and abnormalities associated with its synthesis and excretion seems warranted in a symposium of this sort. Although calcium metabolism and excretion have been investigat...
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| Veröffentlicht in: | Kidney international 1978-05, Vol.13 (5), p.410-417 |
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| creator | Williams, Hibbard E. |
| description | Because calcium oxalate renal stones are the most common type of renal calculus found in this country, a discussion of oxalic acid and abnormalities associated with its synthesis and excretion seems warranted in a symposium of this sort. Although calcium metabolism and excretion have been investigated extensively in syndromes associated with recurrent nephrolithiasis, relatively little attention has been paid to oxalate in these conditions. Nevertheless, information now available, particularly concerning the known hyperoxaluric conditions, has led to greater understanding of idiopathic calcium oxalate nephrolithiasis and more rational treatment of this condition. In this review, the physicochemical and metabolic aspects of oxalic acid will be reviewed, followed by a discussion of the hyperoxaluric syndromes and the role of oxalate in idiopathic calcium oxalate stone disease. |
| doi_str_mv | 10.1038/ki.1978.59 |
| format | Article |
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Although calcium metabolism and excretion have been investigated extensively in syndromes associated with recurrent nephrolithiasis, relatively little attention has been paid to oxalate in these conditions. Nevertheless, information now available, particularly concerning the known hyperoxaluric conditions, has led to greater understanding of idiopathic calcium oxalate nephrolithiasis and more rational treatment of this condition. 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In this review, the physicochemical and metabolic aspects of oxalic acid will be reviewed, followed by a discussion of the hyperoxaluric syndromes and the role of oxalate in idiopathic calcium oxalate stone disease.</description><subject>Adult</subject><subject>Animals</subject><subject>Calcium - urine</subject><subject>Child</subject><subject>Diet</subject><subject>Humans</subject><subject>Kidney Calculi - etiology</subject><subject>Kidney Calculi - physiopathology</subject><subject>Kidney Calculi - therapy</subject><subject>Kidney Calculi - urine</subject><subject>Metabolism, Inborn Errors - complications</subject><subject>Metabolism, Inborn Errors - therapy</subject><subject>Oxalates - metabolism</subject><subject>Oxalates - urine</subject><subject>Syndrome</subject><issn>0085-2538</issn><issn>1523-1755</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkDtPwzAUhS3EqxQWZoZODKAUvx2PqOIlVeoCs-XYN6ppHsVOEP33pErFxHR19H060j0IXRM8J5jlD5swJ1rlc6GP0IQIyjKihDhGE4xzkVHB8nN0kdInHrJm-AydMkGo1BN0v_qxVXAz64Kf2cbPujXM1rstxHYAfRxQ2jU-tjWkS3RS2irB1eFO0cfz0_viNVuuXt4Wj8vMcZp3mQfOeaE9daqQXCsC0lNrmVRYc66ZtBrzQpGSy4LkSuVOSl-IQSJUlxbYFN2OvdvYfvWQOlOH5KCqbANtn4zimEol6SDejaKLbUoRSrONobZxZwg2-2HMJpj9MEboQb45tPZFDf5PHZcYMB8xDJ99B4gmuQCNAx8iuM74NvzX-gsAZm40</recordid><startdate>197805</startdate><enddate>197805</enddate><creator>Williams, Hibbard E.</creator><general>Elsevier Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197805</creationdate><title>Oxalic acid and the hyperoxaluric syndromes</title><author>Williams, Hibbard E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c428t-de444b9d2c7b64971e6d2aa3670944936a904b71f46b18778c66db56d2129fae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1978</creationdate><topic>Adult</topic><topic>Animals</topic><topic>Calcium - urine</topic><topic>Child</topic><topic>Diet</topic><topic>Humans</topic><topic>Kidney Calculi - etiology</topic><topic>Kidney Calculi - physiopathology</topic><topic>Kidney Calculi - therapy</topic><topic>Kidney Calculi - urine</topic><topic>Metabolism, Inborn Errors - complications</topic><topic>Metabolism, Inborn Errors - therapy</topic><topic>Oxalates - metabolism</topic><topic>Oxalates - urine</topic><topic>Syndrome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Williams, Hibbard E.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Kidney international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Williams, Hibbard E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Oxalic acid and the hyperoxaluric syndromes</atitle><jtitle>Kidney international</jtitle><addtitle>Kidney Int</addtitle><date>1978-05</date><risdate>1978</risdate><volume>13</volume><issue>5</issue><spage>410</spage><epage>417</epage><pages>410-417</pages><issn>0085-2538</issn><eissn>1523-1755</eissn><abstract>Because calcium oxalate renal stones are the most common type of renal calculus found in this country, a discussion of oxalic acid and abnormalities associated with its synthesis and excretion seems warranted in a symposium of this sort. 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| ispartof | Kidney international, 1978-05, Vol.13 (5), p.410-417 |
| issn | 0085-2538 1523-1755 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adult Animals Calcium - urine Child Diet Humans Kidney Calculi - etiology Kidney Calculi - physiopathology Kidney Calculi - therapy Kidney Calculi - urine Metabolism, Inborn Errors - complications Metabolism, Inborn Errors - therapy Oxalates - metabolism Oxalates - urine Syndrome |
| title | Oxalic acid and the hyperoxaluric syndromes |
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