Effects of organic acids on tubulin polymerization and associated guanosine 5'-triphosphate hydrolysis

We have examined the effects of a number of organic anions, which stabilize tubulin, on tubulin polymerization, associated GTP hydrolysis, and polymer morphology. While microtubule-associated proteins, as well as glycerol, induced formation of typical microtubules in a reaction coupled to GTP hydrol...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemistry (Easton) 1982-01, Vol.21 (3), p.503-509
Hauptverfasser:	Hamel, E, del Campo, A A, Lowe, M C, Waxman, P G, Lin, C M
Format:	Artikel
Sprache:	eng
Schlagworte:	acids Animals Anions brain Brain - metabolism Cattle GTP GTP Phosphohydrolases - metabolism Guanosine Triphosphate - metabolism Kinetics Macromolecular Substances Microscopy, Electron Microtubule-Associated Proteins Nerve Tissue Proteins - metabolism organic compounds polymerization Proteins - metabolism tubulin Tubulin - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!