ALTERATION OF LYMPHOID CELLS IN AKR MICE BY TREATMENT WITH MONOCLONAL ANTIBODY AGAINST THY-1 ANTIGEN

AKR/J mice treated with high levels of monoclonal anti-Thy-1.1 antibody and C remained healthy without apparent side effects. Examination of the lymphatic organs of these mice demonstrated a selective depletion of T cells in lymph nodes and spleen. Following cessation of treatment of the levels of a...

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Veröffentlicht in:	Transplantation 1982-03, Vol.33 (3), p.269-273
Hauptverfasser:	TAM, MILTON R, BERNSTEIN, IRWIN D, NOWINSKI, ROBERT C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antigen-Antibody Reactions Antigens, Surface - immunology Complement System Proteins - metabolism Cytotoxicity, Immunologic Leukocyte Count Membrane Proteins - immunology Mice Mice, Inbred A Mice, Inbred AKR - immunology Mice, Inbred BALB C Mice, Inbred C57BL Rabbits T-Lymphocytes - immunology Thy-1 Antigens
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