The pharmacokinetics and metabolism of the anilide local anaesthetics in neonates. I. Lignocaine

The pharmacokinetics and metabolism of lignocaine in premature neonates was studied after subcutaneous administration. The collection of serial urine together with a limited number of blood samples from neonates enabled simultaneous computer fitting of data to a pharmacokinetic model. The dispositio...

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Veröffentlicht in:	European journal of clinical pharmacology 1978-05, Vol.13 (2), p.143-152
Hauptverfasser:	Mihaly, G W, Moore, R G, Thomas, J, Triggs, E J, Thomas, D, Shanks, C A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aging Biotransformation Humans Infant, Newborn Intestinal Absorption Kinetics Lidocaine - metabolism Lidocaine - urine Liver - metabolism Male Middle Aged Models, Biological Tissue Distribution
Online-Zugang:	Volltext
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