Effect of Food on the Bioavailability of Captopril in Healthy Subjects

: 14C‐Captopril was administered as 100‐mg tablets to 12 subjects in a two‐way crossover study in which subjects were either fasted or were given a standard meal immediately prior to dosing. Based on blood level and urinary excretion data, both the absorption of total radioactivity and the bioavaila...

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Veröffentlicht in:	Journal of clinical pharmacology 1982-02, Vol.22 (2-3), p.135-140
Hauptverfasser:	SINGHVI, SAMPAT M., McKINSTRY, DORIS N., SHAW, JAMES M., WILLARD, DAVID A., MIGDALOF, BRUCE H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological Availability Biotransformation Captopril - administration & dosage Captopril - metabolism Feces - analysis Food Humans Male Proline - analogs & derivatives Time Factors
Online-Zugang:	Volltext
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