Sulfated glycosaminoglycan and collagen patterns in parietal yolk sac carcinoma (PYSC)
Electrophoretic analyses of collagenous material have shown that the parietal yolk sac carcinoma (PYSC) ascitic tumour synthesizes polypeptide chains that migrate as type IV procollagen. Having molecular weights of 185,000 and 160,000, these polypeptides are sensitive to collagenase. When the PYSC c...
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| Veröffentlicht in: | Cell differentiation 1982-04, Vol.11 (2), p.99-106 |
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| creator | De Fátima Bonaldo, Maria Cassaro-Strunz, Célia M. Machado-Santelli, Gláucia |
| description | Electrophoretic analyses of collagenous material have shown that the parietal yolk sac carcinoma (PYSC) ascitic tumour synthesizes polypeptide chains that migrate as type IV procollagen. Having molecular weights of 185,000 and 160,000, these polypeptides are sensitive to collagenase. When the PYSC cells are injected subcutaneously, they form a solid tumour, and type I collagen predominates. The electrophoretic analyses of sulfated glycosaminoglycans and enzymatic degradation have shown a predominance of heparan sulfate in the ascitic tumour, and of chondroitin sulfate B in the solid tumour. Cells cultured from ascitic tumours have maintained the same collagen and sulfated glycosaminoglycan patterns as the original cells, whereas in the solid tumour culture only chondroitin sulfate AC
∗∗
∗∗
Chondroitin-4,6-sulfate and dermatan sulfate are also known as chondroitin sulfate AC and chondroitin sulfate B, respectively. Chondroitin sulfate is used to designate copolymers of chondroitin-4,6-sulfate and dermatan sulfate.
has been detected. |
| doi_str_mv | 10.1016/0045-6039(82)90024-0 |
| format | Article |
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∗∗
∗∗
Chondroitin-4,6-sulfate and dermatan sulfate are also known as chondroitin sulfate AC and chondroitin sulfate B, respectively. Chondroitin sulfate is used to designate copolymers of chondroitin-4,6-sulfate and dermatan sulfate.
has been detected.</description><identifier>ISSN: 0045-6039</identifier><identifier>DOI: 10.1016/0045-6039(82)90024-0</identifier><identifier>PMID: 6461417</identifier><language>eng</language><publisher>Ireland: Elsevier B.V</publisher><subject>Animals ; Ascites ; basement membrane ; Cells, Cultured ; Chondroitin - analogs & derivatives ; Chondroitin Sulfates - analysis ; Chondroitin Sulfates - biosynthesis ; Collagen - analysis ; Collagen - biosynthesis ; Dermatan Sulfate - analysis ; Glycosaminoglycans - analysis ; Heparitin Sulfate - analysis ; Mesonephroma - analysis ; Mesonephroma - metabolism ; Mice ; Neoplasm Transplantation ; parietal yolk sac carcinoma ; Procollagen - analysis ; sulfated glycosaminoglycan ; type IV collagen</subject><ispartof>Cell differentiation, 1982-04, Vol.11 (2), p.99-106</ispartof><rights>1982</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-1885a62ba4f3cd66377a85f436e2accec0c2d6dca4b0b03470e21b35a45cbd0c3</citedby><cites>FETCH-LOGICAL-c357t-1885a62ba4f3cd66377a85f436e2accec0c2d6dca4b0b03470e21b35a45cbd0c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6461417$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>De Fátima Bonaldo, Maria</creatorcontrib><creatorcontrib>Cassaro-Strunz, Célia M.</creatorcontrib><creatorcontrib>Machado-Santelli, Gláucia</creatorcontrib><title>Sulfated glycosaminoglycan and collagen patterns in parietal yolk sac carcinoma (PYSC)</title><title>Cell differentiation</title><addtitle>Cell Differ</addtitle><description>Electrophoretic analyses of collagenous material have shown that the parietal yolk sac carcinoma (PYSC) ascitic tumour synthesizes polypeptide chains that migrate as type IV procollagen. Having molecular weights of 185,000 and 160,000, these polypeptides are sensitive to collagenase. When the PYSC cells are injected subcutaneously, they form a solid tumour, and type I collagen predominates. The electrophoretic analyses of sulfated glycosaminoglycans and enzymatic degradation have shown a predominance of heparan sulfate in the ascitic tumour, and of chondroitin sulfate B in the solid tumour. Cells cultured from ascitic tumours have maintained the same collagen and sulfated glycosaminoglycan patterns as the original cells, whereas in the solid tumour culture only chondroitin sulfate AC
∗∗
∗∗
Chondroitin-4,6-sulfate and dermatan sulfate are also known as chondroitin sulfate AC and chondroitin sulfate B, respectively. Chondroitin sulfate is used to designate copolymers of chondroitin-4,6-sulfate and dermatan sulfate.
has been detected.</description><subject>Animals</subject><subject>Ascites</subject><subject>basement membrane</subject><subject>Cells, Cultured</subject><subject>Chondroitin - analogs & derivatives</subject><subject>Chondroitin Sulfates - analysis</subject><subject>Chondroitin Sulfates - biosynthesis</subject><subject>Collagen - analysis</subject><subject>Collagen - biosynthesis</subject><subject>Dermatan Sulfate - analysis</subject><subject>Glycosaminoglycans - analysis</subject><subject>Heparitin Sulfate - analysis</subject><subject>Mesonephroma - analysis</subject><subject>Mesonephroma - metabolism</subject><subject>Mice</subject><subject>Neoplasm Transplantation</subject><subject>parietal yolk sac carcinoma</subject><subject>Procollagen - analysis</subject><subject>sulfated glycosaminoglycan</subject><subject>type IV collagen</subject><issn>0045-6039</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLxDAQx3NQfH8DhZxED9WkSdP2IsjiCwQFH-ApTCdTifaxJl1hv72tu3j0NMP85z-PH2OHUpxJIc25EDpLjFDlSZGelkKkOhEbbOevvM12Y_wY60Jm5RbbMtpILfMd9vq0aGoYyPH3Zol9hNZ3_ZRCx6FzHPumgXfq-ByGgUIXuZ_y4GmAhi_75pNHQI4QcDS2wE8e355mp_tss4Ym0sE67rGX66vn2W1y_3BzN7u8T1Bl-ZDIosjApBXoWqEzRuU5FFmtlaEUEAkFps44BF2JSiidC0plpTLQGVZOoNpjx6u589B_LSgOtvURaby5o34Rba7KstRajI161YihjzFQbefBtxCWVgo7IbQTKzuxskVqfxHayXa0nr-oWnJ_pjW_Ub9Y6TQ--e0p2IieOiTnA-FgXe__X_ADotKCnA</recordid><startdate>198204</startdate><enddate>198204</enddate><creator>De Fátima Bonaldo, Maria</creator><creator>Cassaro-Strunz, Célia M.</creator><creator>Machado-Santelli, Gláucia</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198204</creationdate><title>Sulfated glycosaminoglycan and collagen patterns in parietal yolk sac carcinoma (PYSC)</title><author>De Fátima Bonaldo, Maria ; Cassaro-Strunz, Célia M. ; Machado-Santelli, Gláucia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-1885a62ba4f3cd66377a85f436e2accec0c2d6dca4b0b03470e21b35a45cbd0c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Animals</topic><topic>Ascites</topic><topic>basement membrane</topic><topic>Cells, Cultured</topic><topic>Chondroitin - analogs & derivatives</topic><topic>Chondroitin Sulfates - analysis</topic><topic>Chondroitin Sulfates - biosynthesis</topic><topic>Collagen - analysis</topic><topic>Collagen - biosynthesis</topic><topic>Dermatan Sulfate - analysis</topic><topic>Glycosaminoglycans - analysis</topic><topic>Heparitin Sulfate - analysis</topic><topic>Mesonephroma - analysis</topic><topic>Mesonephroma - metabolism</topic><topic>Mice</topic><topic>Neoplasm Transplantation</topic><topic>parietal yolk sac carcinoma</topic><topic>Procollagen - analysis</topic><topic>sulfated glycosaminoglycan</topic><topic>type IV collagen</topic><toplevel>online_resources</toplevel><creatorcontrib>De Fátima Bonaldo, Maria</creatorcontrib><creatorcontrib>Cassaro-Strunz, Célia M.</creatorcontrib><creatorcontrib>Machado-Santelli, Gláucia</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cell differentiation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>De Fátima Bonaldo, Maria</au><au>Cassaro-Strunz, Célia M.</au><au>Machado-Santelli, Gláucia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sulfated glycosaminoglycan and collagen patterns in parietal yolk sac carcinoma (PYSC)</atitle><jtitle>Cell differentiation</jtitle><addtitle>Cell Differ</addtitle><date>1982-04</date><risdate>1982</risdate><volume>11</volume><issue>2</issue><spage>99</spage><epage>106</epage><pages>99-106</pages><issn>0045-6039</issn><abstract>Electrophoretic analyses of collagenous material have shown that the parietal yolk sac carcinoma (PYSC) ascitic tumour synthesizes polypeptide chains that migrate as type IV procollagen. Having molecular weights of 185,000 and 160,000, these polypeptides are sensitive to collagenase. When the PYSC cells are injected subcutaneously, they form a solid tumour, and type I collagen predominates. The electrophoretic analyses of sulfated glycosaminoglycans and enzymatic degradation have shown a predominance of heparan sulfate in the ascitic tumour, and of chondroitin sulfate B in the solid tumour. Cells cultured from ascitic tumours have maintained the same collagen and sulfated glycosaminoglycan patterns as the original cells, whereas in the solid tumour culture only chondroitin sulfate AC
∗∗
∗∗
Chondroitin-4,6-sulfate and dermatan sulfate are also known as chondroitin sulfate AC and chondroitin sulfate B, respectively. Chondroitin sulfate is used to designate copolymers of chondroitin-4,6-sulfate and dermatan sulfate.
has been detected.</abstract><cop>Ireland</cop><pub>Elsevier B.V</pub><pmid>6461417</pmid><doi>10.1016/0045-6039(82)90024-0</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Cell differentiation, 1982-04, Vol.11 (2), p.99-106 |
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| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Ascites basement membrane Cells, Cultured Chondroitin - analogs & derivatives Chondroitin Sulfates - analysis Chondroitin Sulfates - biosynthesis Collagen - analysis Collagen - biosynthesis Dermatan Sulfate - analysis Glycosaminoglycans - analysis Heparitin Sulfate - analysis Mesonephroma - analysis Mesonephroma - metabolism Mice Neoplasm Transplantation parietal yolk sac carcinoma Procollagen - analysis sulfated glycosaminoglycan type IV collagen |
| title | Sulfated glycosaminoglycan and collagen patterns in parietal yolk sac carcinoma (PYSC) |
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