mRNA Levels of the hypoxia inducible factor (HIF-1) and DNA repair genes in perinatal asphyxia of the rat

Hypoxia inducible factor 1 (HIF-1) is a transcription factor which is expressed, when mammalian cells are subjected to hypoxia, activating the transcription of genes encoding proteins thought important for maintaining oxygen hemostasis. The aim of the study was to evaluate HIF-1 mRNA levels in a non...

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Veröffentlicht in:	Life sciences (1973) 1998, Vol.63 (13), p.1157-1167
Hauptverfasser:	Chiappe-Gutierrez, Marina, Kitzmueller, Erwin, Labudova, Olga, Fuerst, Gerhard, Hoeger, Harald, Hardmeier, Rosmarie, Nohl, Hans, Gille, Lars, Lubec, Barbara
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Asphyxia - metabolism Brain - metabolism catalase Catalase - genetics DNA Helicases DNA repair DNA Repair - genetics DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - genetics Drosophila Proteins Electron Spin Resonance Spectroscopy ESR Female glutathion peroxidase Glutathione Peroxidase - genetics Hydrogen-Ion Concentration Hydroxyl Radical - metabolism hypoxia Hypoxia-Inducible Factor 1 Hypoxia-Inducible Factor 1, alpha Subunit neonatal Nuclear Proteins - biosynthesis Pregnancy Proteins - genetics Rats Rats, Sprague-Dawley RNA, Messenger - metabolism Superoxide dismutase Superoxide Dismutase - genetics TEMPO Transcription Factors X-ray Repair Cross Complementing Protein 1 Xeroderma Pigmentosum Group D Protein
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