Lichen nitidus: electron microscopic and immunofluorescence studies
Skin biopsies from a patient suffering from lichen nitidus were studied by electron microscopy and immunofluorescence studies. Complete disintegration of the stratum basale in the central area of the lesion and signs of acantholysis in the border area were found. In the central part of the lesion th...
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| Veröffentlicht in: | Acta dermato-venereologica 1982, Vol.62 (1), p.15-19 |
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| container_title | Acta dermato-venereologica |
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| creator | Clausen, J Jacobsen, F K Brandrup, F |
| description | Skin biopsies from a patient suffering from lichen nitidus were studied by electron microscopy and immunofluorescence studies. Complete disintegration of the stratum basale in the central area of the lesion and signs of acantholysis in the border area were found. In the central part of the lesion the dermo-epidermal junction was severely damaged in most places. In the dermal infiltrate, macrophages and lymphocytes were found with a considerable representation of Sézary cells, not previously reported in lichen nitidus. The ultrastructural changes are identical with those found in lichen planus. No in vivo bound immunoglobulins, fibrinogen, or complement C3 were found. |
| doi_str_mv | 10.2340/00015555621519 |
| format | Article |
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Complete disintegration of the stratum basale in the central area of the lesion and signs of acantholysis in the border area were found. In the central part of the lesion the dermo-epidermal junction was severely damaged in most places. In the dermal infiltrate, macrophages and lymphocytes were found with a considerable representation of Sézary cells, not previously reported in lichen nitidus. The ultrastructural changes are identical with those found in lichen planus. No in vivo bound immunoglobulins, fibrinogen, or complement C3 were found.</description><identifier>ISSN: 0001-5555</identifier><identifier>EISSN: 1651-2057</identifier><identifier>DOI: 10.2340/00015555621519</identifier><identifier>PMID: 6175131</identifier><language>eng</language><publisher>Sweden</publisher><subject>Adolescent ; Fluorescent Antibody Technique ; Humans ; Male ; Microscopy, Electron ; Skin - ultrastructure ; Skin Diseases - diagnosis ; Skin Diseases - immunology ; Skin Diseases - pathology</subject><ispartof>Acta dermato-venereologica, 1982, Vol.62 (1), p.15-19</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c330t-b612c44a49335d3d179b7558c304304aef447663fcdc582f68ed5d6d0b663e2e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6175131$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Clausen, J</creatorcontrib><creatorcontrib>Jacobsen, F K</creatorcontrib><creatorcontrib>Brandrup, F</creatorcontrib><title>Lichen nitidus: electron microscopic and immunofluorescence studies</title><title>Acta dermato-venereologica</title><addtitle>Acta Derm Venereol</addtitle><description>Skin biopsies from a patient suffering from lichen nitidus were studied by electron microscopy and immunofluorescence studies. Complete disintegration of the stratum basale in the central area of the lesion and signs of acantholysis in the border area were found. In the central part of the lesion the dermo-epidermal junction was severely damaged in most places. In the dermal infiltrate, macrophages and lymphocytes were found with a considerable representation of Sézary cells, not previously reported in lichen nitidus. The ultrastructural changes are identical with those found in lichen planus. No in vivo bound immunoglobulins, fibrinogen, or complement C3 were found.</description><subject>Adolescent</subject><subject>Fluorescent Antibody Technique</subject><subject>Humans</subject><subject>Male</subject><subject>Microscopy, Electron</subject><subject>Skin - ultrastructure</subject><subject>Skin Diseases - diagnosis</subject><subject>Skin Diseases - immunology</subject><subject>Skin Diseases - pathology</subject><issn>0001-5555</issn><issn>1651-2057</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVUE1LxDAQDaKs6-rVm9CTt66ZfLX1JotfUPCi59ImU4y0zZo0B_-9KbsIDgPDzHvzmHmEXAPdMi7oHaUUZArFQEJ1QtagJOSMyuKUrBcwX9BzchHCV2qZhHJFVgoKCRzWZFdb_YlTNtnZmhjuMxxQz95N2Wi1d0G7vdVZO5nMjmOcXD9E5zFonDRmYY7GYrgkZ307BLw61g35eHp8373k9dvz6-6hzjXndM47BUwL0YqKc2m4gaLqCilLzalI2WIvRKEU77XRsmS9KtFIowzt0hAZ8g25PejuvfuOGOZmtOmSYWgndDE0Ba9KBYIl4vZAXD4IHvtm7-3Y-p8GaLO41vx3LS3cHJVjN6L5ox9t4r8zL2bA</recordid><startdate>1982</startdate><enddate>1982</enddate><creator>Clausen, J</creator><creator>Jacobsen, F K</creator><creator>Brandrup, F</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1982</creationdate><title>Lichen nitidus: electron microscopic and immunofluorescence studies</title><author>Clausen, J ; Jacobsen, F K ; Brandrup, F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c330t-b612c44a49335d3d179b7558c304304aef447663fcdc582f68ed5d6d0b663e2e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Adolescent</topic><topic>Fluorescent Antibody Technique</topic><topic>Humans</topic><topic>Male</topic><topic>Microscopy, Electron</topic><topic>Skin - ultrastructure</topic><topic>Skin Diseases - diagnosis</topic><topic>Skin Diseases - immunology</topic><topic>Skin Diseases - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Clausen, J</creatorcontrib><creatorcontrib>Jacobsen, F K</creatorcontrib><creatorcontrib>Brandrup, F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta dermato-venereologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Clausen, J</au><au>Jacobsen, F K</au><au>Brandrup, F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lichen nitidus: electron microscopic and immunofluorescence studies</atitle><jtitle>Acta dermato-venereologica</jtitle><addtitle>Acta Derm Venereol</addtitle><date>1982</date><risdate>1982</risdate><volume>62</volume><issue>1</issue><spage>15</spage><epage>19</epage><pages>15-19</pages><issn>0001-5555</issn><eissn>1651-2057</eissn><abstract>Skin biopsies from a patient suffering from lichen nitidus were studied by electron microscopy and immunofluorescence studies. Complete disintegration of the stratum basale in the central area of the lesion and signs of acantholysis in the border area were found. In the central part of the lesion the dermo-epidermal junction was severely damaged in most places. In the dermal infiltrate, macrophages and lymphocytes were found with a considerable representation of Sézary cells, not previously reported in lichen nitidus. The ultrastructural changes are identical with those found in lichen planus. No in vivo bound immunoglobulins, fibrinogen, or complement C3 were found.</abstract><cop>Sweden</cop><pmid>6175131</pmid><doi>10.2340/00015555621519</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Acta dermato-venereologica, 1982, Vol.62 (1), p.15-19 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adolescent Fluorescent Antibody Technique Humans Male Microscopy, Electron Skin - ultrastructure Skin Diseases - diagnosis Skin Diseases - immunology Skin Diseases - pathology |
| title | Lichen nitidus: electron microscopic and immunofluorescence studies |
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