Novel Alternative Splice Variants of cGMP-binding cGMP-specific Phosphodiesterase

After our recent findings that the amino-terminal portion of rat cGMP-binding, cGMP-specific phosphodiesterase (cGB-PDE) differs from those of bovine and human cGB-PDEs, we found two forms of canine cGB-PDE cDNAs (CFPDE5A1 and CFPDE5A2) in canine lung. Each contained a distinct amino-terminal sequen...

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Veröffentlicht in:	The Journal of biological chemistry 1998-10, Vol.273 (41), p.26982-26990
Hauptverfasser:	Kotera, Jun, Fujishige, Kotomi, Akatsuka, Hiroyuki, Imai, Yuji, Yanaka, Noriyuki, Omori, Kenji
Format:	Artikel
Sprache:	eng
Schlagworte:	3',5'-Cyclic-GMP Phosphodiesterases - chemistry 3',5'-Cyclic-GMP Phosphodiesterases - genetics 3',5'-Cyclic-GMP Phosphodiesterases - metabolism Alternative Splicing Amino Acid Sequence Animals Base Sequence Cloning, Molecular COS Cells Cyclic GMP - metabolism DNA Primers Dogs Humans Kinetics Male Molecular Sequence Data Phosphodiesterase Inhibitors - pharmacology Protein Binding Recombinant Proteins - chemistry Recombinant Proteins - genetics Recombinant Proteins - metabolism Reverse Transcriptase Polymerase Chain Reaction Sequence Homology, Amino Acid Subcellular Fractions - metabolism
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