Rats Self-Administer Nonrewarding Brain Stimulation to Ameliorate Aversion

Rats Self-Administer Nonrewarding Brain Stimulation to Ameliorate Aversion

Hypothalamic stimulation in rats both reduces escape from noxious hindbrain stimulation and sustains self-administration only when hindbrain stimulation is inescapable. Self-administration reflects an aversion-ameliorative action of brain stimulation and not a positive reinforcement process. The psy...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1982-03, Vol.215 (4539), p.1516-1517
Hauptverfasser: Carr, Kenneth D., Coons, Edgar E.
Format: Artikel
Sprache:eng
Schlagworte:
Analgesia
Animals
Avoidance Learning - physiology
Brain research
Electrodes
Experimentation
Hypothalamus - physiology
Mental stimulation
Motivation
Nociceptive pain
Pain
Pain - physiopathology
Rats
Self Administration
Skull
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container_issue 4539
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container_title Science (American Association for the Advancement of Science)
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creator Carr, Kenneth D.
Coons, Edgar E.
description Hypothalamic stimulation in rats both reduces escape from noxious hindbrain stimulation and sustains self-administration only when hindbrain stimulation is inescapable. Self-administration reflects an aversion-ameliorative action of brain stimulation and not a positive reinforcement process. The psychophysical testing used is offered as a model for establishing the analgesic properties of brain stimulation.
doi_str_mv 10.1126/science.7063859
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subjects Analgesia
Animals
Avoidance Learning - physiology
Brain research
Electrodes
Experimentation
Hypothalamus - physiology
Mental stimulation
Motivation
Nociceptive pain
Pain
Pain - physiopathology
Rats
Self Administration
Skull
title Rats Self-Administer Nonrewarding Brain Stimulation to Ameliorate Aversion
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