Metoclopramide reduces the distress associated with colon cleansing by an oral electrolyte overload
A randomized, double-blind clinical trial compared the effect of placebo and 10 mg metoclopramide on reducing the distress associated with colon cleansing using an oral electrolyte overload method. Up to 75% of controls experienced no or mild distress. Metociopramide significantly reduced bloating (...
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Veröffentlicht in: | Gastrointestinal endoscopy 1978-05, Vol.24 (4), p.162-163 |
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container_title | Gastrointestinal endoscopy |
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creator | Rhodes, James B. Engstrom, John Stone, Kathleen F. |
description | A randomized, double-blind clinical trial compared the effect of placebo and 10 mg metoclopramide on reducing the distress associated with colon cleansing using an oral electrolyte overload method. Up to 75% of controls experienced no or mild distress. Metociopramide significantly reduced bloating (p |
doi_str_mv | 10.1016/S0016-5107(78)73495-4 |
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Up to 75% of controls experienced no or mild distress. Metociopramide significantly reduced bloating (p<0.005) and nausea (p<0.025). Cramps and vomiting were reduced, but did not attain statistical significance. 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Up to 75% of controls experienced no or mild distress. Metociopramide significantly reduced bloating (p<0.005) and nausea (p<0.025). Cramps and vomiting were reduced, but did not attain statistical significance. Satisfactory cleansing was obtained in 90% of the cases in 2 to 4 hours.</description><subject>Clinical Trials as Topic</subject><subject>Colon</subject><subject>Double-Blind Method</subject><subject>Endoscopy</subject><subject>Humans</subject><subject>Metoclopramide - therapeutic use</subject><subject>Water-Electrolyte Imbalance - drug therapy</subject><issn>0016-5107</issn><issn>1097-6779</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtPBCEQhInxtT7-gSacjB5GYRiG4WSM8ZVoPKhngk2PYthhBVaz_97RNV69dB-qqiv9EbLP2TFnvD15YOOsJGfqUHVHSjRaVs0KmXCmVdUqpVfJ5M-ySbZyfmOMdbXgG2RdNJ2U3YTAHZYIIc6SnXqHNKGbA2ZaXpE6n0vCnKnNOYK3BR399OWVQgxxoBDQDtkPL_R5Qe1AY7KBYkAoKYZFQRo_MIVo3Q5Z623IuPu7t8nT5cXj-XV1e391c352W4GQulQKrAXGXK9ZJ0BYAb0SVkqmEVStm1Z0knOsGQoxOpjq2xpEp3iPqlZoxTY5WN6dpfg-x1zM1GfAEOyAcZ6NElrqpm5Ho1waIcWcE_ZmlvzUpoXhzHyzNT9szTc4ozrzw9Y0Y27vt2D-PEX3l1rCHOXTpYzjkx8ek8ngcQB0Po1UjIv-n4Ivj0qKIQ</recordid><startdate>197805</startdate><enddate>197805</enddate><creator>Rhodes, James B.</creator><creator>Engstrom, John</creator><creator>Stone, Kathleen F.</creator><general>Mosby, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197805</creationdate><title>Metoclopramide reduces the distress associated with colon cleansing by an oral electrolyte overload</title><author>Rhodes, James B. ; Engstrom, John ; Stone, Kathleen F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-7caac00df9083c3a3cf73a5509ec7294638511e20e3308307f62c3871fe727ea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1978</creationdate><topic>Clinical Trials as Topic</topic><topic>Colon</topic><topic>Double-Blind Method</topic><topic>Endoscopy</topic><topic>Humans</topic><topic>Metoclopramide - therapeutic use</topic><topic>Water-Electrolyte Imbalance - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rhodes, James B.</creatorcontrib><creatorcontrib>Engstrom, John</creatorcontrib><creatorcontrib>Stone, Kathleen F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Gastrointestinal endoscopy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rhodes, James B.</au><au>Engstrom, John</au><au>Stone, Kathleen F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metoclopramide reduces the distress associated with colon cleansing by an oral electrolyte overload</atitle><jtitle>Gastrointestinal endoscopy</jtitle><addtitle>Gastrointest Endosc</addtitle><date>1978-05</date><risdate>1978</risdate><volume>24</volume><issue>4</issue><spage>162</spage><epage>163</epage><pages>162-163</pages><issn>0016-5107</issn><eissn>1097-6779</eissn><abstract>A randomized, double-blind clinical trial compared the effect of placebo and 10 mg metoclopramide on reducing the distress associated with colon cleansing using an oral electrolyte overload method. 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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Clinical Trials as Topic Colon Double-Blind Method Endoscopy Humans Metoclopramide - therapeutic use Water-Electrolyte Imbalance - drug therapy |
title | Metoclopramide reduces the distress associated with colon cleansing by an oral electrolyte overload |
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