Effects of recombinant human bone morphogenetic protein-2 on differentiation of cells isolated from human bone, muscle, and skin

We investigated the effects of recombinant human BMP-2 (rhBMP-2) on differentiation of cells isolated from human bone, muscle, and skin. Cells isolated from bones of six patients (HBM-1 to HBM-6), muscle from five patients (HM-1 to HM-5), and skin from three patients (HF-1 to HF-3) were used. rhBMP-...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 1998-09, Vol.23 (3), p.223-231
Hauptverfasser:	Kawasaki, K., Aihara, M., Honmo, J., Sakurai, S., Fujimaki, Y., Sakamoto, K., Fujimaki, E., Wozney, J.M., Yamaguchi, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - metabolism Animals Biological and medical sciences Bone Marrow Cells - cytology Bone morphogenetic protein Bone Morphogenetic Protein 2 Bone Morphogenetic Proteins - pharmacology Calcitriol - pharmacology Cell culture Cell Differentiation - drug effects Cell Transplantation Cells, Cultured Cyclic AMP - metabolism Diffusion Chambers, Culture Fundamental and applied biological sciences. Psychology Human Humans Ilium - drug effects Mice Mice, Nude Muscle Muscles - drug effects Osteoblasts Osteocalcin - metabolism Parathyroid Hormone Recombinant Proteins - pharmacology Skeleton and joints Skin - drug effects Transforming Growth Factor beta - pharmacology Vertebrates: osteoarticular system, musculoskeletal system
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