Numbers and differentiation status of melanocytes in idiopathic guttate hypomelanosis

The etiology and pathogenesis of idiopathic guttate hypomelanosis (IGH) are largely unknown. To investigate whether the pathologic alteration in IGH involves changes in melanocytic differentiation, cell number, or both, we studied nine lesions of IGH by immunoperoxidase, using monoclonal antibodies...

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Veröffentlicht in:	Journal of cutaneous pathology 1998-08, Vol.25 (7), p.375-379
Hauptverfasser:	Wallaces, Michael L., Grichnik, James M., Prieto, Victor G., Shea, Christopher R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cell Differentiation Dermatology Fluorescent Antibody Technique, Indirect Humans Hypopigmentation - metabolism Hypopigmentation - pathology Hypopigmentation - physiopathology Immunoenzyme Techniques Medical sciences Melanocytes - cytology Melanocytes - metabolism Melanocytes - pathology Membrane Glycoproteins Oxidoreductases Pigmentary diseases of the skin Proteins - metabolism Skin - metabolism Skin - pathology Skin - physiopathology Skin Diseases - metabolism Skin Diseases - pathology Skin Diseases - physiopathology
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