The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway

Theiler's murine encephalomyelitis virus (TMEV) infection of a susceptible strain of mice results in virus persistence in the brain and chronic primary immune-mediated demyelination, which resembles multiple sclerosis. Recent attention has focused on the anti-inflammatory and immunosuppressive...

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Veröffentlicht in:	FEBS letters 1998-08, Vol.433 (1), p.139-142
Hauptverfasser:	Molina-Holgado, Francisco, Molina-Holgado, Eduardo, Guaza, Carmen
Format:	Artikel
Sprache:	eng
Schlagworte:	Anandamide Animals Arachidonic Acids - pharmacology Astrocyte Astrocytes - metabolism Astrocytes - virology Cannabinoid Cannabinoids - pharmacology Cells, Cultured Cerebral Cortex - cytology Endocannabinoids Fluorescent Antibody Technique Interleukin-6 Interleukin-6 - biosynthesis Mice Mice, Inbred BALB C Poliomyelitis - virology Polyunsaturated Alkamides Receptors, Cannabinoid Receptors, Drug - physiology Theiler's virus Theilovirus - physiology
Online-Zugang:	Volltext
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