cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3)

Previously, we cloned rat MRP3 as a candidate for an inducible transporter for the biliary excretion of organic anions [Hirohashi et al. (1998) Mol. Pharmacol. 53, 1068–1075]. In the present study, we cloned human MRP3 (1527 amino acids) from Caco-2 cells. Human MRP3 is predominantly expressed in li...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	FEBS letters 1998-08, Vol.433 (1), p.149-152
Hauptverfasser:	Kiuchi, Yuichi, Suzuki, Hiroshi, Hirohashi, Tomoko, Tyson, Charles A, Sugiyama, Yuichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence ATP-Binding Cassette Transporters - chemistry ATP-Binding Cassette Transporters - genetics Biliary excretion Blotting, Northern Caco-2 Cells Canalicular multispecific organic anion transporter Carcinoma, Hepatocellular Cloning, Molecular Colon - chemistry DNA, Complementary - genetics Gene Expression - drug effects GS-X pump Humans Intestine, Small - chemistry Liver - chemistry Liver Neoplasms Molecular Sequence Data Multidrug resistance Multidrug resistance associated protein Multidrug Resistance-Associated Proteins Phenobarbital - pharmacology Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!