The Medium Subunits of Adaptor Complexes Recognize Distinct but Overlapping Sets of Tyrosine-based Sorting Signals

Tyrosine-based sorting signals conforming to the motif YXXØ (Y is tyrosine, X is any amino acid, and Ø is an amino acid with a bulky hydrophobic side chain (leucine, isoleucine, phenylalanine, methionine, valine)) interact with the medium (μ) subunits of clathrin adaptor (AP) complexes. We have anal...

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Veröffentlicht in:	The Journal of biological chemistry 1998-10, Vol.273 (40), p.25915-25921
Hauptverfasser:	Ohno, Hiroshi, Aguilar, Ruben C., Yeh, David, Taura, Daisuke, Saito, Takashi, Bonifacino, Juan S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Protein Complex 1 Adaptor Protein Complex 2 Adaptor Protein Complex 3 Adaptor Protein Complex mu Subunits Adaptor Proteins, Vesicular Transport Amino Acid Sequence Animals Endocytosis - physiology Endosomes - metabolism Gene Library Lysosomes - metabolism Membrane Proteins - chemistry Molecular Sequence Data Monomeric Clathrin Assembly Proteins Nerve Tissue Proteins - chemistry Phosphoproteins - chemistry Protein Sorting Signals - chemistry Tyrosine - chemistry Vertebrates
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