Protective role of Anacardium occidentale extract against streptozotocin-induced diabetes in rats
The protective effect of Anacardium occidentale aqueous extract against streptozotocin-induced diabetes was evaluated in rats. The rats were treated with 175 mg/kg of the extract per os, twice daily; beginning 2 days before streptozotocin (STZ) injection. A total of 3 days after STZ administration,...
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| Veröffentlicht in: | Journal of ethnopharmacology 1998-09, Vol.62 (2), p.95-99 |
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| container_end_page | 99 |
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| container_title | Journal of ethnopharmacology |
| container_volume | 62 |
| creator | Kamtchouing, Pierre Sokeng, Selestin D Moundipa, Paul F Watcho, Pierre Jatsa, Hermine B Lontsi, David |
| description | The protective effect of
Anacardium occidentale aqueous extract against streptozotocin-induced diabetes was evaluated in rats. The rats were treated with 175 mg/kg of the extract per os, twice daily; beginning 2 days before streptozotocin (STZ) injection. A total of 3 days after STZ administration, there was a 48% increase in blood glucose level in pretreated rats, compared with a 208% increase in diabetic control rats treated with STZ alone. Furthermore, these pretreated animals presented no glycosuria, a normal weight gain and a non significant increase in food and fluid intake at the end of the treatment compared with the normal control. Diabetic control animals showed a positive glycosuria, body weight loss, a real polyphagia and polydypsia. These results indicate the protective role of
Anacardium occidentale extract against the diabetogenic action of STZ. |
| doi_str_mv | 10.1016/S0378-8741(97)00159-1 |
| format | Article |
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Anacardium occidentale aqueous extract against streptozotocin-induced diabetes was evaluated in rats. The rats were treated with 175 mg/kg of the extract per os, twice daily; beginning 2 days before streptozotocin (STZ) injection. A total of 3 days after STZ administration, there was a 48% increase in blood glucose level in pretreated rats, compared with a 208% increase in diabetic control rats treated with STZ alone. Furthermore, these pretreated animals presented no glycosuria, a normal weight gain and a non significant increase in food and fluid intake at the end of the treatment compared with the normal control. Diabetic control animals showed a positive glycosuria, body weight loss, a real polyphagia and polydypsia. These results indicate the protective role of
Anacardium occidentale extract against the diabetogenic action of STZ.</description><identifier>ISSN: 0378-8741</identifier><identifier>EISSN: 1872-7573</identifier><identifier>DOI: 10.1016/S0378-8741(97)00159-1</identifier><identifier>PMID: 9741880</identifier><identifier>CODEN: JOETD7</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Anacardium occidentale ; Animals ; Biological and medical sciences ; Blood Glucose - analysis ; Diabetes mellitus ; Diabetes Mellitus, Experimental - blood ; Diabetes Mellitus, Experimental - prevention & control ; experimental diabetes ; General pharmacology ; Male ; Medical sciences ; medicinal plants ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; Plant Extracts - pharmacology ; Plants, Medicinal - chemistry ; Rats ; Rats, Wistar ; Streptozocin ; Streptozotocin ; traditional medicine</subject><ispartof>Journal of ethnopharmacology, 1998-09, Vol.62 (2), p.95-99</ispartof><rights>1998 Elsevier Science Ireland Ltd</rights><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c510t-87c6a781d4ccd5b09d1c8d19c805d7298839d03cbee9d8d0c3af759073c174193</citedby><cites>FETCH-LOGICAL-c510t-87c6a781d4ccd5b09d1c8d19c805d7298839d03cbee9d8d0c3af759073c174193</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0378-8741(97)00159-1$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2407415$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9741880$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kamtchouing, Pierre</creatorcontrib><creatorcontrib>Sokeng, Selestin D</creatorcontrib><creatorcontrib>Moundipa, Paul F</creatorcontrib><creatorcontrib>Watcho, Pierre</creatorcontrib><creatorcontrib>Jatsa, Hermine B</creatorcontrib><creatorcontrib>Lontsi, David</creatorcontrib><title>Protective role of Anacardium occidentale extract against streptozotocin-induced diabetes in rats</title><title>Journal of ethnopharmacology</title><addtitle>J Ethnopharmacol</addtitle><description>The protective effect of
Anacardium occidentale aqueous extract against streptozotocin-induced diabetes was evaluated in rats. The rats were treated with 175 mg/kg of the extract per os, twice daily; beginning 2 days before streptozotocin (STZ) injection. A total of 3 days after STZ administration, there was a 48% increase in blood glucose level in pretreated rats, compared with a 208% increase in diabetic control rats treated with STZ alone. Furthermore, these pretreated animals presented no glycosuria, a normal weight gain and a non significant increase in food and fluid intake at the end of the treatment compared with the normal control. Diabetic control animals showed a positive glycosuria, body weight loss, a real polyphagia and polydypsia. These results indicate the protective role of
Anacardium occidentale extract against the diabetogenic action of STZ.</description><subject>Anacardium occidentale</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Blood Glucose - analysis</subject><subject>Diabetes mellitus</subject><subject>Diabetes Mellitus, Experimental - blood</subject><subject>Diabetes Mellitus, Experimental - prevention & control</subject><subject>experimental diabetes</subject><subject>General pharmacology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>medicinal plants</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>Plant Extracts - pharmacology</subject><subject>Plants, Medicinal - chemistry</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Streptozocin</subject><subject>Streptozotocin</subject><subject>traditional medicine</subject><issn>0378-8741</issn><issn>1872-7573</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkV1rFDEUhoModa3-hOJciOjF6MlkpkmuSil-QUGh9jqcPTlTIrOTNckU9deb7S5726sDeZ_zkfcV4kzCBwny_OMNKG1ao3v5zur3AHKwrXwiVtLortWDVk_F6og8Fy9y_gUAWvZwIk5sfTMGVgJ_pFiYSrjnJsWJmzg2lzMSJh-WTROJgue5YFX4T0lIpcE7DHMuTS6JtyX-iyVSmNsw-4XYNz7gmgvnJsxNwpJfimcjTplfHeqpuP386efV1_b6-5dvV5fXLQ0SSr2SzlEb6XsiP6zBeknGS0sGBq87a4yyHhStma03HkjhqAcLWpGsn7HqVLzdz92m-HvhXNwmZOJpwpnjkp1WtlPWwKOg1NIo1e8mDnuQUsw58ei2KWww_XUS3C4D95CB2xnsrHYPGThZ-84OC5b1hv2x62B61d8cdMyE05hwppCPWNdDBYeKvd5jI0aHd6kitzcdSAWdMUNnukpc7Amuvt4HTi5T4LmmEFLN1PkYHjn1P_kwrUE</recordid><startdate>19980901</startdate><enddate>19980901</enddate><creator>Kamtchouing, Pierre</creator><creator>Sokeng, Selestin D</creator><creator>Moundipa, Paul F</creator><creator>Watcho, Pierre</creator><creator>Jatsa, Hermine B</creator><creator>Lontsi, David</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>19980901</creationdate><title>Protective role of Anacardium occidentale extract against streptozotocin-induced diabetes in rats</title><author>Kamtchouing, Pierre ; Sokeng, Selestin D ; Moundipa, Paul F ; Watcho, Pierre ; Jatsa, Hermine B ; Lontsi, David</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c510t-87c6a781d4ccd5b09d1c8d19c805d7298839d03cbee9d8d0c3af759073c174193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Anacardium occidentale</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Blood Glucose - analysis</topic><topic>Diabetes mellitus</topic><topic>Diabetes Mellitus, Experimental - blood</topic><topic>Diabetes Mellitus, Experimental - prevention & control</topic><topic>experimental diabetes</topic><topic>General pharmacology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>medicinal plants</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>Plant Extracts - pharmacology</topic><topic>Plants, Medicinal - chemistry</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Streptozocin</topic><topic>Streptozotocin</topic><topic>traditional medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kamtchouing, Pierre</creatorcontrib><creatorcontrib>Sokeng, Selestin D</creatorcontrib><creatorcontrib>Moundipa, Paul F</creatorcontrib><creatorcontrib>Watcho, Pierre</creatorcontrib><creatorcontrib>Jatsa, Hermine B</creatorcontrib><creatorcontrib>Lontsi, David</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of ethnopharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kamtchouing, Pierre</au><au>Sokeng, Selestin D</au><au>Moundipa, Paul F</au><au>Watcho, Pierre</au><au>Jatsa, Hermine B</au><au>Lontsi, David</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Protective role of Anacardium occidentale extract against streptozotocin-induced diabetes in rats</atitle><jtitle>Journal of ethnopharmacology</jtitle><addtitle>J Ethnopharmacol</addtitle><date>1998-09-01</date><risdate>1998</risdate><volume>62</volume><issue>2</issue><spage>95</spage><epage>99</epage><pages>95-99</pages><issn>0378-8741</issn><eissn>1872-7573</eissn><coden>JOETD7</coden><abstract>The protective effect of
Anacardium occidentale aqueous extract against streptozotocin-induced diabetes was evaluated in rats. The rats were treated with 175 mg/kg of the extract per os, twice daily; beginning 2 days before streptozotocin (STZ) injection. A total of 3 days after STZ administration, there was a 48% increase in blood glucose level in pretreated rats, compared with a 208% increase in diabetic control rats treated with STZ alone. Furthermore, these pretreated animals presented no glycosuria, a normal weight gain and a non significant increase in food and fluid intake at the end of the treatment compared with the normal control. Diabetic control animals showed a positive glycosuria, body weight loss, a real polyphagia and polydypsia. These results indicate the protective role of
Anacardium occidentale extract against the diabetogenic action of STZ.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>9741880</pmid><doi>10.1016/S0378-8741(97)00159-1</doi><tpages>5</tpages></addata></record> |
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| issn | 0378-8741 1872-7573 |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Anacardium occidentale Animals Biological and medical sciences Blood Glucose - analysis Diabetes mellitus Diabetes Mellitus, Experimental - blood Diabetes Mellitus, Experimental - prevention & control experimental diabetes General pharmacology Male Medical sciences medicinal plants Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - pharmacology Plants, Medicinal - chemistry Rats Rats, Wistar Streptozocin Streptozotocin traditional medicine |
| title | Protective role of Anacardium occidentale extract against streptozotocin-induced diabetes in rats |
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