Immunodiagnosis of late, recurrent retinoblastoma

The clinical, pathological, and immunohistochemical features of a patient with bilateral retinoblastoma who developed a nasopharyngeal mass seven years following irradiation treatment of the left eye is described. Diagnosis of the new tumor was difficult by routine light microscopy. Immunohistochemi...

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Veröffentlicht in:Retina (Philadelphia, Pa.) Pa.), 1981, Vol.1 (2), p.107-112
Hauptverfasser: Donoso, L A, Felberg, N T, Shields, J A, Martyn, L J, Wimmer, R S
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container_title Retina (Philadelphia, Pa.)
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creator Donoso, L A
Felberg, N T
Shields, J A
Martyn, L J
Wimmer, R S
description The clinical, pathological, and immunohistochemical features of a patient with bilateral retinoblastoma who developed a nasopharyngeal mass seven years following irradiation treatment of the left eye is described. Diagnosis of the new tumor was difficult by routine light microscopy. Immunohistochemical staining of the original globes, the nasopharyngeal mass, and a cervical lymph node biopsy specimen with an antiserum prepared against tissue cultured retinoblastoma cells suggested the diagnosis of metastatic retinoblastoma rather than a "radiation-induced" sarcoma.
doi_str_mv 10.1097/00006982-198101020-00006
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subjects Child
Child, Preschool
Eye Neoplasms - diagnosis
Eye Neoplasms - pathology
Eye Neoplasms - radiotherapy
Humans
Infant
Lymph Nodes - pathology
Male
Neoplasm Metastasis
Retinoblastoma - diagnosis
Retinoblastoma - pathology
Retinoblastoma - radiotherapy
title Immunodiagnosis of late, recurrent retinoblastoma
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