Vasoactive intestinal peptide shortens both G1 and S phases of neural cell cycle in whole postimplantation cultured mouse embryos

Vasoactive intestinal peptide, a trophic and mitogenic factor, stimulates growth in whole cultured mouse embryos. Inhibition of this growth function between embryonic days 9 and 11 induces growth retardation accompanied by severe microcephaly. In the present study, to determine the effects of this p...

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Veröffentlicht in:	The European journal of neuroscience 1998-05, Vol.10 (5), p.1734-1742
Hauptverfasser:	Gressens, Pierre, Paindaveine, Bénédicte, Hill, Joanna M., Evrard, Philippe, Brenneman, Douglas E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Culture Techniques Embryo, Mammalian - cytology Embryo, Mammalian - drug effects Embryonic and Fetal Development - drug effects Embryonic Development Epithelial Cells - drug effects Female G1 Phase - drug effects growth factor Mice Nervous System - cytology Nervous System - drug effects Nervous System - embryology neuroepithelium neurogenesis pituitary adenylate cyclase activating polypeptide Pregnancy S Phase - drug effects Vasoactive Intestinal Peptide - pharmacology
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