Aberrant Expression of a Cytokeratin in a Subset of Hepatocytes during Chronic WHV Infection

Chronic infection of woodchucks with woodchuck hepatitis virus (WHV) invariably leads, within 2–4 years, to the appearance of hepatocellular carcinoma (HCC). HCC is preceded by an extended period of chronic liver damage, probably resulting from the immune response to viral antigens. It may be that i...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1998-09, Vol.249 (1), p.68-79
Hauptverfasser:	Pugh, John C., Guo, Ju-Tao, Aldrich, Carol, Rall, Glenn, Kajino, Kazunori, Tennant, Bud, England, James M., Mason, William S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Chronic Disease Female Hepatitis B - metabolism Hepatitis B - pathology Hepatitis B Virus, Woodchuck Immunohistochemistry Keratins - biosynthesis Liver - metabolism Liver - pathology Mice Mice, Inbred BALB C
Online-Zugang:	Volltext
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