Phenanthroline-Cu complex-mediated chemiluminescence of DNA and its potential use in antioxidation evaluation

The chemiluminescence (CL) concomitant with phen-Cu 2+ /ascorbate/H 2O 2-induced DNA damage has been studied. The emission intensity increases linearly with increasing DNA concentration. The emission spectrum has a maximal wavelength at about 410 nm. The luminescence is inhibited by histone in a his...

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Veröffentlicht in:	Journal of photochemistry and photobiology. B, Biology Biology, 1998-06, Vol.44 (1), p.63-68
Hauptverfasser:	Ma, Wenjian, Cao, En-Hua, Zhang, Jian, Qin, Jing-Fen
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Antioxidants - pharmacology Chemiluminescence Copper - pharmacology DNA - chemistry DNA - drug effects DNA Damage Guanine Intercalating Agents - pharmacology Kinetics Luminescent Measurements Oxidative stress Phenanthroline-Cu 2+ complex Phenanthrolines - pharmacology Reactive oxygen species
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