Functional characterization of ORCTL2 - an organic cation transporter expressed in the renal proximal tubules

Chromosome 11p15.5 harbors a gene or genes involved in Beckwith-Wiedemann syndrome that confer(s) susceptibility to Wilms' tumor, rhabdomyosarcoma, and hepatoblastoma. We have previously identified a transcript at 11p15.5 which encodes a putative membrane transport protein, designated organic c...

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Veröffentlicht in:	FEBS letters 1998-08, Vol.433 (3), p.245-250
Hauptverfasser:	Reece, Mark, Prawitt, Dirk, Landers, John, Kast, Christina, Gros, Philippe, Housman, David, Zabel, Bernhard U., Pelletier, Jerry
Format:	Artikel
Sprache:	eng
Schlagworte:	11p15.5 Animals Bacteria - genetics Base Sequence Beckwith-Wiedemann syndrome Beckwith-Wiedemann Syndrome - genetics Biological Transport Carrier Proteins - biosynthesis Carrier Proteins - genetics Carrier Proteins - physiology Chloroquine - pharmacokinetics Chromosome Mapping Chromosomes, Human, Pair 11 COS Cells Drug Resistance, Multiple - genetics Humans Kidney Tubules, Proximal - metabolism Kinetics Membrane Proteins - biosynthesis Membrane Proteins - genetics Membrane Proteins - physiology Molecular Sequence Data Oligodeoxyribonucleotides Organic Cation Transport Proteins Organic cation transporter Organic cation transporter like-2 Quinidine - pharmacokinetics Recombinant Proteins - metabolism Tetracycline - pharmacokinetics Tetracycline Resistance - genetics Tetracycline/H + antiporter Transcription, Genetic Transfection
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