A model of autosomal recessive Alport syndrome in English cocker spaniel dogs

A model of autosomal recessive Alport syndrome in English cocker spaniel dogs. Dogs with naturally occurring genetic disorders of basement membrane (type IV) collagen may serve as animal models of Alport syndrome. An autosomal recessive form of progressive hereditary nephritis (HN) was studied in 10...

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Veröffentlicht in:	Kidney international 1998-09, Vol.54 (3), p.706-719
Hauptverfasser:	Lees, George E., Helman, R. Gayman, Kashtan, Clifford E., Michael, Alfred F., Homco, Linda D., Millichamp, Nicholas J., Ninomiya, Yoshifumi, Sado, Yoshikazu, Naito, Ichiro, Kim, Youngki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals basement membrane Biological and medical sciences chronic renal failure Collagen - analysis Disease Models, Animal Dogs Female genetic disorder Glomerulonephritis hereditary nephritis Humans Immunohistochemistry Kidney - chemistry Kidney - pathology Kidney - ultrastructure Male Medical sciences multilamination Nephritis, Hereditary - metabolism Nephritis, Hereditary - pathology Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure progressive glomerular disease type IV collagen
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