Sensitization of cells to ionizing radiation by chlorin e6Na

We have investigated whether a hydrophilic photosensitizer, chlorin e6Na (Ce6Na), can sensitize cells to ionizing radiation. When V79‐1 cells were pretreated with Ce6Na for 2 hr before receiving a dose of 2–14 Gy of irradiation, the cells became sensitive to X‐irradiation. The sensitizing effect of...

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Veröffentlicht in:	Radiation oncology investigations 1998, Vol.6 (4), p.151-156
Hauptverfasser:	Hosoi, Yoshio, Kawamura, Mieko, Ido, Tatsuo, Takai, Yoshihiro, Ishii, Keiichiro, Nemoto, Kenji, Ono, Tetuya, Kimura, Shuichi, Sakamoto, Kiyohiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured chlorin e6Na Cricetinae Cricetulus Fibroblasts - drug effects Fibroblasts - radiation effects hematoporphyrin Lung - cytology Porphyrins - pharmacology Radiation, Ionizing Radiation-Sensitizing Agents - pharmacology sensitizer X-irradiation X-Rays - adverse effects
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