Population pharmacokinetic analysis of mexiletine in adult arrhythmic patients in Japanese population

We analyzed mexiletine in Japanese patients using population pharmacokinetics. 139 serum concentration data, which were collected for therapeutic drug monitoring from 121 patients, were used for this analysis. We also investigated influence of age and gender on pharmacokinetics, and age was found to...

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Veröffentlicht in:Biological & pharmaceutical bulletin 1998, Vol.21 (8), p.844-846
Hauptverfasser: UENAKA, K, KOUE, T, IWAI, T, SHIBAKAWA, M, UENO, K
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Sprache:eng
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