Isolation of Avian Reovirus as a Possible Etiologic Agent of Osteoporosis ("Brittle Bone Disease"; "Femoral Head Necrosis") in Broiler Chickens

Avian reovirus was isolated from intestines of 3-to-7-day-old broiler chickens with enteritis from broiler houses where osteoporosis was a problem. The virus was purified in a cesium chloride gradient (buoyant density 1.37 gm/ml) and identified as a reovirus by electron microscopy. Specific-pathogen...

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