Electromechanical coupling in human vas deferens: effects of agents that modulate intracellular release of calcium

Summary The effects of ryanodine, cyclopiazonic acid (CPA) and caffeine on electromechanical coupling in human vas deferens were investigated. High [K+]o (120 mM) evoked nifedipine‐sensitive contractions of longitudinal and circular muscle which consisted of initial and secondary components. Exposur...

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Veröffentlicht in:	Journal of autonomic pharmacology 1998-06, Vol.18 (3), p.157-165
Hauptverfasser:	Amobi, N. I. B., Smith, I. C. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Caffeine - pharmacology Calcium - metabolism Calcium Channel Blockers - pharmacology Calcium-Transporting ATPases - antagonists & inhibitors Enzyme Inhibitors - pharmacology Humans In Vitro Techniques Indoles - pharmacology Male Muscle Contraction - drug effects Nifedipine - pharmacology Ryanodine - pharmacology Vas Deferens - drug effects Vas Deferens - physiology
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