Identification of CSF-1 as a brain macrophage migratory activity produced by astrocytes

Intraparenchymal migration of macrophages occurs in the CNS during development or as a consequence of tissue injuries. In the present study, we have shown, by using an in vitro chemotaxis assay, that cultured rat astrocytes obtained from the developing cerebral cortex and striatum produce soluble fa...

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Veröffentlicht in:	Glia 1998-10, Vol.24 (2), p.180-186
Hauptverfasser:	Calvo, Charles-Félix, Dobbertin, Alexandre, Gelman, Michèle, Glowinski, Jacques, Mallat, Michel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes - metabolism Biological and medical sciences Blotting, Northern Brain - cytology Brain Chemistry - physiology Cell Division - physiology Cell Movement - physiology Cell Survival - physiology Cells, Cultured chemoattraction Chemotaxis, Leukocyte - physiology cytokine Cytokines - biosynthesis Enzyme-Linked Immunosorbent Assay Fundamental and applied biological sciences. Psychology Humans Isolated neuron and nerve. Neuroglia Macrophage Colony-Stimulating Factor - biosynthesis Macrophage Colony-Stimulating Factor - physiology Macrophages - metabolism microglia Neurons - metabolism Rats Vertebrates: nervous system and sense organs
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