Abruptio placentae

Analysis of blood samples from pregnant women has shown that the mean histamine level starts to rise when the plasma ascorbic acid level falls below 1.0 mg/100 ml; it is doubled when the ascorbate level falls to 0.5 mg/100 ml and quadrupled when it falls below 0.2 mg/100 ml. The incidence of abrupti...

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Veröffentlicht in:International journal of gynecology and obstetrics 1981-12, Vol.19 (6), p.453-460
Hauptverfasser: Clemetson, C.Alan B., Cafaro, Virginia
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container_issue 6
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container_title International journal of gynecology and obstetrics
container_volume 19
creator Clemetson, C.Alan B.
Cafaro, Virginia
description Analysis of blood samples from pregnant women has shown that the mean histamine level starts to rise when the plasma ascorbic acid level falls below 1.0 mg/100 ml; it is doubled when the ascorbate level falls to 0.5 mg/100 ml and quadrupled when it falls below 0.2 mg/100 ml. The incidence of abruptio placentae was found to be seven out of 355 (or 2.0%) in women who had plasma ascorbic acid levels above 0.4 mg/100 ml and six out of 31 (19.4%) in women with plasma ascorbate levels below 0.4 mg/100 ml. This difference is highly significant. It is suggested that ascorbic acid deficiency and histamine excess play leading roles in the etiology of abruptio placentae.
doi_str_mv 10.1016/0020-7292(81)90004-7
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ispartof International journal of gynecology and obstetrics, 1981-12, Vol.19 (6), p.453-460
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source MEDLINE; Elsevier ScienceDirect Journals; Wiley-Blackwell Full Collection
subjects Abruptio placentae
Abruptio Placentae - blood
Abruptio Placentae - etiology
Adult
Anemia, Megaloblastic - blood
Ascorbic Acid Deficiency - blood
Ascorbic Acid Deficiency - complications
Female
Folate deficiency
Folic Acid - blood
Histamine - blood
Histamine excess
Humans
Megaloblastic anemia
Plasma ascorbic acid levels
Pregnancy
Vitamin C
title Abruptio placentae
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