Abruptio placentae
Analysis of blood samples from pregnant women has shown that the mean histamine level starts to rise when the plasma ascorbic acid level falls below 1.0 mg/100 ml; it is doubled when the ascorbate level falls to 0.5 mg/100 ml and quadrupled when it falls below 0.2 mg/100 ml. The incidence of abrupti...
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Veröffentlicht in: | International journal of gynecology and obstetrics 1981-12, Vol.19 (6), p.453-460 |
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container_title | International journal of gynecology and obstetrics |
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creator | Clemetson, C.Alan B. Cafaro, Virginia |
description | Analysis of blood samples from pregnant women has shown that the mean histamine level starts to rise when the plasma ascorbic acid level falls below 1.0 mg/100 ml; it is doubled when the ascorbate level falls to 0.5 mg/100 ml and quadrupled when it falls below 0.2 mg/100 ml. The incidence of abruptio placentae was found to be seven out of 355 (or 2.0%) in women who had plasma ascorbic acid levels above 0.4 mg/100 ml and six out of 31 (19.4%) in women with plasma ascorbate levels below 0.4 mg/100 ml. This difference is highly significant. It is suggested that ascorbic acid deficiency and histamine excess play leading roles in the etiology of abruptio placentae. |
doi_str_mv | 10.1016/0020-7292(81)90004-7 |
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The incidence of abruptio placentae was found to be seven out of 355 (or 2.0%) in women who had plasma ascorbic acid levels above 0.4 mg/100 ml and six out of 31 (19.4%) in women with plasma ascorbate levels below 0.4 mg/100 ml. This difference is highly significant. 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The incidence of abruptio placentae was found to be seven out of 355 (or 2.0%) in women who had plasma ascorbic acid levels above 0.4 mg/100 ml and six out of 31 (19.4%) in women with plasma ascorbate levels below 0.4 mg/100 ml. This difference is highly significant. It is suggested that ascorbic acid deficiency and histamine excess play leading roles in the etiology of abruptio placentae.</description><subject>Abruptio placentae</subject><subject>Abruptio Placentae - blood</subject><subject>Abruptio Placentae - etiology</subject><subject>Adult</subject><subject>Anemia, Megaloblastic - blood</subject><subject>Ascorbic Acid Deficiency - blood</subject><subject>Ascorbic Acid Deficiency - complications</subject><subject>Female</subject><subject>Folate deficiency</subject><subject>Folic Acid - blood</subject><subject>Histamine - blood</subject><subject>Histamine excess</subject><subject>Humans</subject><subject>Megaloblastic anemia</subject><subject>Plasma ascorbic acid levels</subject><subject>Pregnancy</subject><subject>Vitamin C</subject><issn>0020-7292</issn><issn>1879-3479</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkL1PwzAQxS0EKqWwMIPEhGAI-GzHHwtSVfFRVKkLzFbiXCSjtAl2Cup_T0Kqjojphnu_d_ceIRdA74CCvKeU0UQxw2403BpKqUjUARmDVibhQplDMt5LjslJjB-dBhTAiIwkMFBMjcn5NA-bpvX1VVNlDtdthqfkqMyqiGe7OSHvT49vs5dksXyez6aLxHHGeHdCSkO10YCMOsGxdKlLTeZAoHSscNqkNNd5mRZcMKWk4SLjTCLylBrJ-IRcD75NqD83GFu78tFhVWVrrDfRKq4NSKo6oRiELtQxBixtE_wqC1sL1PZV2D6n7XNaDfa3Cttjlzv_Tb7CYg_tsnd7M-y_fYXbf3na-evzUqS8Yx8GFruCvjwGG53HtcPCB3StLWr_93M_vu56Tg</recordid><startdate>198112</startdate><enddate>198112</enddate><creator>Clemetson, C.Alan B.</creator><creator>Cafaro, Virginia</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198112</creationdate><title>Abruptio placentae</title><author>Clemetson, C.Alan B. ; Cafaro, Virginia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3223-3466908981e20c43efc5c59ac14e6c2dc8950b8bf5d342776934a326ee3509623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Abruptio placentae</topic><topic>Abruptio Placentae - blood</topic><topic>Abruptio Placentae - etiology</topic><topic>Adult</topic><topic>Anemia, Megaloblastic - blood</topic><topic>Ascorbic Acid Deficiency - blood</topic><topic>Ascorbic Acid Deficiency - complications</topic><topic>Female</topic><topic>Folate deficiency</topic><topic>Folic Acid - blood</topic><topic>Histamine - blood</topic><topic>Histamine excess</topic><topic>Humans</topic><topic>Megaloblastic anemia</topic><topic>Plasma ascorbic acid levels</topic><topic>Pregnancy</topic><topic>Vitamin C</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Clemetson, C.Alan B.</creatorcontrib><creatorcontrib>Cafaro, Virginia</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of gynecology and obstetrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Clemetson, C.Alan B.</au><au>Cafaro, Virginia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Abruptio placentae</atitle><jtitle>International journal of gynecology and obstetrics</jtitle><addtitle>Int J Gynaecol Obstet</addtitle><date>1981-12</date><risdate>1981</risdate><volume>19</volume><issue>6</issue><spage>453</spage><epage>460</epage><pages>453-460</pages><issn>0020-7292</issn><eissn>1879-3479</eissn><abstract>Analysis of blood samples from pregnant women has shown that the mean histamine level starts to rise when the plasma ascorbic acid level falls below 1.0 mg/100 ml; it is doubled when the ascorbate level falls to 0.5 mg/100 ml and quadrupled when it falls below 0.2 mg/100 ml. 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subjects | Abruptio placentae Abruptio Placentae - blood Abruptio Placentae - etiology Adult Anemia, Megaloblastic - blood Ascorbic Acid Deficiency - blood Ascorbic Acid Deficiency - complications Female Folate deficiency Folic Acid - blood Histamine - blood Histamine excess Humans Megaloblastic anemia Plasma ascorbic acid levels Pregnancy Vitamin C |
title | Abruptio placentae |
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