An Area within Human Ventral Cortex Sensitive to “Building” Stimuli: Evidence and Implications

Isolated, ventral brain lesions in humans occasionally produce specific impairments in the ability to use landmarks, particularly buildings, for way-finding. Using functional MRI, we tested the hypothesis that there exists a cortical region specialized for the perception of buildings. Across subject...

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Veröffentlicht in:Neuron (Cambridge, Mass.) Mass.), 1998-08, Vol.21 (2), p.373-383
Hauptverfasser: Aguirre, Geoffrey K, Zarahn, E, D’Esposito, M
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Zarahn, E
D’Esposito, M
description Isolated, ventral brain lesions in humans occasionally produce specific impairments in the ability to use landmarks, particularly buildings, for way-finding. Using functional MRI, we tested the hypothesis that there exists a cortical region specialized for the perception of buildings. Across subjects, a region straddling the right lingual sulcus was identified that possessed the functional correlates predicted for a specialized building area. A series of experiments discounted several alternative explanations for the behavior of this site. These results are discussed in terms of their impact upon our understanding of the functional structure of visual processing, disorders of topographical disorientation, and the influence of environmental conditions upon neural organization.
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subjects Adolescent
Adult
Analysis of Variance
Brain Mapping
Cerebral Cortex - physiology
Cues
Female
Gyrus Cinguli - physiology
Humans
Magnetic Resonance Imaging
Male
Photic Stimulation
title An Area within Human Ventral Cortex Sensitive to “Building” Stimuli: Evidence and Implications
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