A Heterotrimeric G Protein of the Gi Family Is Required for cAMP-triggered Trafficking of Aquaporin 2 in Kidney Epithelial Cells

Vasopressin is the key regulator of water homeostasis in vertebrates. Central to its antidiuretic action in mammals is the redistribution of the water channel aquaporin 2 (AQP2) from intracellular vesicles to the apical membrane of kidney epithelial cells, an event initiated by an increase in cAMP a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 1998-08, Vol.273 (35), p.22627-22634
Hauptverfasser:	Valenti, Giovanna, Procino, Giuseppe, Liebenhoff, Ursula, Frigeri, Antonio, Benedetti, Pio Alberto, Ahnert-Hilger, Gudrun, Nürnberg, Bernd, Svelto, Maria, Rosenthal, Walter
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Aquaporin 2 Aquaporin 6 Aquaporins Biological Transport Cell Line Colforsin - antagonists & inhibitors Colforsin - pharmacology Cyclic AMP - metabolism DNA, Complementary Epithelial Cells - drug effects Epithelial Cells - metabolism GTP-Binding Proteins - metabolism Ion Channels - metabolism Kidney Tubules, Collecting - cytology Kidney Tubules, Collecting - drug effects Kidney Tubules, Collecting - metabolism Microscopy, Confocal Microscopy, Fluorescence Pertussis Toxin Rabbits Rats Virulence Factors, Bordetella - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!