A Case of Active Sarcoid Mimicking a Mediastinal Parathyroid Adenoma on Tc-99m Sestamibi Imaging

A 45-year-old man with a history of parathyroidectomy with a tissue implant in his forearm to treat hyperparathyroidism developed recurrent hyperparathyroidism with a parathyroid hormone level > 3,000 pcm/L. Dual-phase Tc-99m sestamibi imaging was interpreted as showing a persistent retrosternal...

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Veröffentlicht in:Clinical nuclear medicine 1998-08, Vol.23 (8), p.534-535
Hauptverfasser: KLIEGER, PETER, O'MARA, ROBERT
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O'MARA, ROBERT
description A 45-year-old man with a history of parathyroidectomy with a tissue implant in his forearm to treat hyperparathyroidism developed recurrent hyperparathyroidism with a parathyroid hormone level > 3,000 pcm/L. Dual-phase Tc-99m sestamibi imaging was interpreted as showing a persistent retrosternal focus consistent with a mediastinal parathyroid adenoma. The suspected tissue was resected by mediastinoscopy, and pathologic examination revealed chronic inflammatory and granulomatous mediastinal lymph nodes consistent with active sarcoidosis. The patient's parathyroid hormone level promptly returned to normal after removal of parathyroid tissue from his forearm implant, which was markedly hyperplastic on histologic examination.
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source MEDLINE; Journals@Ovid Complete
subjects Adenoma - diagnostic imaging
Biological and medical sciences
Diagnosis, Differential
Endocrinopathies
Humans
Male
Medical sciences
Middle Aged
Non tumoral diseases. Target tissue resistance. Benign neoplasms
Parathyroid Neoplasms - diagnostic imaging
Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases)
Radionuclide Imaging
Radiopharmaceuticals
Sarcoidosis - diagnostic imaging
Technetium Tc 99m Sestamibi
title A Case of Active Sarcoid Mimicking a Mediastinal Parathyroid Adenoma on Tc-99m Sestamibi Imaging
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