A Case of Active Sarcoid Mimicking a Mediastinal Parathyroid Adenoma on Tc-99m Sestamibi Imaging
A 45-year-old man with a history of parathyroidectomy with a tissue implant in his forearm to treat hyperparathyroidism developed recurrent hyperparathyroidism with a parathyroid hormone level > 3,000 pcm/L. Dual-phase Tc-99m sestamibi imaging was interpreted as showing a persistent retrosternal...
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Veröffentlicht in: | Clinical nuclear medicine 1998-08, Vol.23 (8), p.534-535 |
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description | A 45-year-old man with a history of parathyroidectomy with a tissue implant in his forearm to treat hyperparathyroidism developed recurrent hyperparathyroidism with a parathyroid hormone level > 3,000 pcm/L. Dual-phase Tc-99m sestamibi imaging was interpreted as showing a persistent retrosternal focus consistent with a mediastinal parathyroid adenoma. The suspected tissue was resected by mediastinoscopy, and pathologic examination revealed chronic inflammatory and granulomatous mediastinal lymph nodes consistent with active sarcoidosis. The patient's parathyroid hormone level promptly returned to normal after removal of parathyroid tissue from his forearm implant, which was markedly hyperplastic on histologic examination. |
doi_str_mv | 10.1097/00003072-199808000-00011 |
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Dual-phase Tc-99m sestamibi imaging was interpreted as showing a persistent retrosternal focus consistent with a mediastinal parathyroid adenoma. The suspected tissue was resected by mediastinoscopy, and pathologic examination revealed chronic inflammatory and granulomatous mediastinal lymph nodes consistent with active sarcoidosis. The patient's parathyroid hormone level promptly returned to normal after removal of parathyroid tissue from his forearm implant, which was markedly hyperplastic on histologic examination.</description><identifier>ISSN: 0363-9762</identifier><identifier>EISSN: 1536-0229</identifier><identifier>DOI: 10.1097/00003072-199808000-00011</identifier><identifier>PMID: 9712390</identifier><identifier>CODEN: CNMEDK</identifier><language>eng</language><publisher>Philadelphia, PA: Lippincott-Raven Publishers</publisher><subject>Adenoma - diagnostic imaging ; Biological and medical sciences ; Diagnosis, Differential ; Endocrinopathies ; Humans ; Male ; Medical sciences ; Middle Aged ; Non tumoral diseases. Target tissue resistance. Benign neoplasms ; Parathyroid Neoplasms - diagnostic imaging ; Parathyroids. Parafollicular cells. Cholecalciferol. 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Dual-phase Tc-99m sestamibi imaging was interpreted as showing a persistent retrosternal focus consistent with a mediastinal parathyroid adenoma. The suspected tissue was resected by mediastinoscopy, and pathologic examination revealed chronic inflammatory and granulomatous mediastinal lymph nodes consistent with active sarcoidosis. The patient's parathyroid hormone level promptly returned to normal after removal of parathyroid tissue from his forearm implant, which was markedly hyperplastic on histologic examination.</description><subject>Adenoma - diagnostic imaging</subject><subject>Biological and medical sciences</subject><subject>Diagnosis, Differential</subject><subject>Endocrinopathies</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Non tumoral diseases. Target tissue resistance. Benign neoplasms</subject><subject>Parathyroid Neoplasms - diagnostic imaging</subject><subject>Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases)</subject><subject>Radionuclide Imaging</subject><subject>Radiopharmaceuticals</subject><subject>Sarcoidosis - diagnostic imaging</subject><subject>Technetium Tc 99m Sestamibi</subject><issn>0363-9762</issn><issn>1536-0229</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kVtPGzEQRq2KCgLtT6jkB8Tbtr5sfHmMIqBIoFaCPruT2VnishewNyD-fQ1J81ZLljWa89mjY8a4FF-l8PabKEsLqyrpvROuVFXZUn5gMznXphJK-QM2E9roylujjthxzn8KYaSpD9mht1JpL2bs94IvIRMfW77AKT4Tv4WEY2z4TewjPsThngO_oSZCnuIAHf8JCab1a3pjFg0NYw98HPgdVt73_JbyBH1cRX7Vw31Jf2IfW-gyfd6dJ-zXxfnd8nt1_ePyarm4rlC7WlYrhaAMOJwjCtu2RI1UzgtStm0EISC1TmoBZq60AwBEpUFQIayvldUn7Gx772ManzZlitDHjNR1MNC4ycFqZ3xtfQHdFsQ05pyoDY8p9pBegxThTW74Jzfs5YZ3uSX6ZffGZtVTsw_ubJb-6a4PGaFrEwwY8x5T2iitXcHqLfYydhOl_NBtXiiFNUE3rcP_vlb_BV4ukG0</recordid><startdate>199808</startdate><enddate>199808</enddate><creator>KLIEGER, PETER</creator><creator>O'MARA, ROBERT</creator><general>Lippincott-Raven Publishers</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199808</creationdate><title>A Case of Active Sarcoid Mimicking a Mediastinal Parathyroid Adenoma on Tc-99m Sestamibi Imaging</title><author>KLIEGER, PETER ; O'MARA, ROBERT</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3841-b2ca26a8c5cc07ffeed12890e27fd0ecacef8130a65238aaacc23a0e90e794273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Adenoma - diagnostic imaging</topic><topic>Biological and medical sciences</topic><topic>Diagnosis, Differential</topic><topic>Endocrinopathies</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Non tumoral diseases. Target tissue resistance. Benign neoplasms</topic><topic>Parathyroid Neoplasms - diagnostic imaging</topic><topic>Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases)</topic><topic>Radionuclide Imaging</topic><topic>Radiopharmaceuticals</topic><topic>Sarcoidosis - diagnostic imaging</topic><topic>Technetium Tc 99m Sestamibi</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KLIEGER, PETER</creatorcontrib><creatorcontrib>O'MARA, ROBERT</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical nuclear medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KLIEGER, PETER</au><au>O'MARA, ROBERT</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Case of Active Sarcoid Mimicking a Mediastinal Parathyroid Adenoma on Tc-99m Sestamibi Imaging</atitle><jtitle>Clinical nuclear medicine</jtitle><addtitle>Clin Nucl Med</addtitle><date>1998-08</date><risdate>1998</risdate><volume>23</volume><issue>8</issue><spage>534</spage><epage>535</epage><pages>534-535</pages><issn>0363-9762</issn><eissn>1536-0229</eissn><coden>CNMEDK</coden><abstract>A 45-year-old man with a history of parathyroidectomy with a tissue implant in his forearm to treat hyperparathyroidism developed recurrent hyperparathyroidism with a parathyroid hormone level > 3,000 pcm/L. Dual-phase Tc-99m sestamibi imaging was interpreted as showing a persistent retrosternal focus consistent with a mediastinal parathyroid adenoma. The suspected tissue was resected by mediastinoscopy, and pathologic examination revealed chronic inflammatory and granulomatous mediastinal lymph nodes consistent with active sarcoidosis. The patient's parathyroid hormone level promptly returned to normal after removal of parathyroid tissue from his forearm implant, which was markedly hyperplastic on histologic examination.</abstract><cop>Philadelphia, PA</cop><cop>Hagerstown, MD</cop><pub>Lippincott-Raven Publishers</pub><pmid>9712390</pmid><doi>10.1097/00003072-199808000-00011</doi><tpages>2</tpages></addata></record> |
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subjects | Adenoma - diagnostic imaging Biological and medical sciences Diagnosis, Differential Endocrinopathies Humans Male Medical sciences Middle Aged Non tumoral diseases. Target tissue resistance. Benign neoplasms Parathyroid Neoplasms - diagnostic imaging Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases) Radionuclide Imaging Radiopharmaceuticals Sarcoidosis - diagnostic imaging Technetium Tc 99m Sestamibi |
title | A Case of Active Sarcoid Mimicking a Mediastinal Parathyroid Adenoma on Tc-99m Sestamibi Imaging |
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