Phospholamban Modulates Murine Atrial Contractile Parameters and Responses toβ-Adrenergic Agonists

Phospholamban gene transcript levels are much lower in murine atria as compared to murine ventricles and this reduced phospholamban expression has been suggested to result in enhanced atrial contractile parameters. To delineate the functional role of phospholamban in murine atrium, the contractile p...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 1998-07, Vol.30 (7), p.1275-1284
Hauptverfasser:	Kadambi, Vivek J, Koss, Kimberly L, Grupp, Ingrid L, Kranias, Evangelia G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Agonists - pharmacology Animals Atrial Function Atrium Calcium-Binding Proteins - genetics Calcium-Binding Proteins - physiology Female Genetically engineered mice Heart Atria - drug effects Isoproterenol - pharmacology Mice Mice, Knockout Myocardial Contraction - drug effects Myocardial Contraction - physiology Phospholamban Relaxation β-agonists
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