Lipoprotein electrophoresis in fat embolism: a preliminary report
Serum lipoprotein electrophoresis and other laboratory tests were made on 14 injured patients over 10 days. Reduction in the pre-beta fraction to an average of 6 per cent, with an elevation of the alpha lipoprotein fraction to an average of 41 per cent, were recorded. The patients without complicati...
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| Veröffentlicht in: | Injury 1981-09, Vol.13 (2), p.108-110 |
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| container_title | Injury |
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| creator | Treiman, Noam Waisbrod, Vita Waisbrod, Hannan |
| description | Serum lipoprotein electrophoresis and other laboratory tests were made on 14 injured patients over 10 days. Reduction in the pre-beta fraction to an average of 6 per cent, with an elevation of the alpha lipoprotein fraction to an average of 41 per cent, were recorded. The patients without complications regained their normal lipoprotein pattern within 48 hours, while in the two cases who developed fat embolism, the deranged pattern lasted for up to 10 days.
The clinical diagnosis of fat embolism is based on signs that appear generally within 3 days following injury.
As prognosis depends on early diagnosis, in order to start treatment before full blown clinical signs are present, there is the need for a laboratory test which gives early results and is reliable and easy to perform.
This study shows an apparently distinct pattern of the serum lipoproteins which may provide us with a warning about which patients are at risk of developing fat embolism. |
| doi_str_mv | 10.1016/0020-1383(81)90043-7 |
| format | Article |
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The clinical diagnosis of fat embolism is based on signs that appear generally within 3 days following injury.
As prognosis depends on early diagnosis, in order to start treatment before full blown clinical signs are present, there is the need for a laboratory test which gives early results and is reliable and easy to perform.
This study shows an apparently distinct pattern of the serum lipoproteins which may provide us with a warning about which patients are at risk of developing fat embolism.</description><identifier>ISSN: 0020-1383</identifier><identifier>EISSN: 1879-0267</identifier><identifier>DOI: 10.1016/0020-1383(81)90043-7</identifier><identifier>PMID: 7327722</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Blood Protein Electrophoresis ; Electrophoresis, Agar Gel ; Embolism, Fat - blood ; Embolism, Fat - etiology ; Female ; Femoral Fractures - blood ; Fractures, Bone - blood ; Fractures, Closed - blood ; Fractures, Closed - complications ; Humans ; Lipoproteins - blood ; Lumbar Vertebrae - injuries ; Male ; Middle Aged ; Pelvic Bones - injuries ; Tibial Fractures - blood</subject><ispartof>Injury, 1981-09, Vol.13 (2), p.108-110</ispartof><rights>1981</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-58d943a5d5466d978a7005c7f685122a1f81017d578da1189dff2109162de3cf3</citedby><cites>FETCH-LOGICAL-c357t-58d943a5d5466d978a7005c7f685122a1f81017d578da1189dff2109162de3cf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0020-1383(81)90043-7$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27907,27908,45978</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7327722$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Treiman, Noam</creatorcontrib><creatorcontrib>Waisbrod, Vita</creatorcontrib><creatorcontrib>Waisbrod, Hannan</creatorcontrib><title>Lipoprotein electrophoresis in fat embolism: a preliminary report</title><title>Injury</title><addtitle>Injury</addtitle><description>Serum lipoprotein electrophoresis and other laboratory tests were made on 14 injured patients over 10 days. Reduction in the pre-beta fraction to an average of 6 per cent, with an elevation of the alpha lipoprotein fraction to an average of 41 per cent, were recorded. The patients without complications regained their normal lipoprotein pattern within 48 hours, while in the two cases who developed fat embolism, the deranged pattern lasted for up to 10 days.
The clinical diagnosis of fat embolism is based on signs that appear generally within 3 days following injury.
As prognosis depends on early diagnosis, in order to start treatment before full blown clinical signs are present, there is the need for a laboratory test which gives early results and is reliable and easy to perform.
This study shows an apparently distinct pattern of the serum lipoproteins which may provide us with a warning about which patients are at risk of developing fat embolism.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Blood Protein Electrophoresis</subject><subject>Electrophoresis, Agar Gel</subject><subject>Embolism, Fat - blood</subject><subject>Embolism, Fat - etiology</subject><subject>Female</subject><subject>Femoral Fractures - blood</subject><subject>Fractures, Bone - blood</subject><subject>Fractures, Closed - blood</subject><subject>Fractures, Closed - complications</subject><subject>Humans</subject><subject>Lipoproteins - blood</subject><subject>Lumbar Vertebrae - injuries</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pelvic Bones - injuries</subject><subject>Tibial Fractures - blood</subject><issn>0020-1383</issn><issn>1879-0267</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhoMotVb_gcKeRA-r-dhssh6EUvyCghc9hzSZYGR3syZbwX9vakuPngZm3nnnnQehc4JvCCb1LcYUl4RJdiXJdYNxxUpxgKZEiqbEtBaHaLqXHKOTlD4xJgIzNkETwagQlE7RfOmHMMQwgu8LaMGMMQwfIULyqcgtp8cCulVoferuCl0MEVrf-V7HnyLCEOJ4io6cbhOc7eoMvT8-vC2ey-Xr08tiviwN42IsubRNxTS3vKpr2wipBcbcCFdLTijVxMn8lbBcSKsJkY11jhLckJpaYMaxGbrc-ua0X2tIo-p8MtC2uoewTkowyVldNVlYbYUmhpQiODVE3-XAimC1Iac2WNQGi5JE_ZHL2zN0sfNfrzqw-6Udqjy_384hP_ntIapkPPQGrI8Zm7LB_3_gFyNyfBU</recordid><startdate>198109</startdate><enddate>198109</enddate><creator>Treiman, Noam</creator><creator>Waisbrod, Vita</creator><creator>Waisbrod, Hannan</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198109</creationdate><title>Lipoprotein electrophoresis in fat embolism: a preliminary report</title><author>Treiman, Noam ; Waisbrod, Vita ; Waisbrod, Hannan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-58d943a5d5466d978a7005c7f685122a1f81017d578da1189dff2109162de3cf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Blood Protein Electrophoresis</topic><topic>Electrophoresis, Agar Gel</topic><topic>Embolism, Fat - blood</topic><topic>Embolism, Fat - etiology</topic><topic>Female</topic><topic>Femoral Fractures - blood</topic><topic>Fractures, Bone - blood</topic><topic>Fractures, Closed - blood</topic><topic>Fractures, Closed - complications</topic><topic>Humans</topic><topic>Lipoproteins - blood</topic><topic>Lumbar Vertebrae - injuries</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pelvic Bones - injuries</topic><topic>Tibial Fractures - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Treiman, Noam</creatorcontrib><creatorcontrib>Waisbrod, Vita</creatorcontrib><creatorcontrib>Waisbrod, Hannan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Injury</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Treiman, Noam</au><au>Waisbrod, Vita</au><au>Waisbrod, Hannan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lipoprotein electrophoresis in fat embolism: a preliminary report</atitle><jtitle>Injury</jtitle><addtitle>Injury</addtitle><date>1981-09</date><risdate>1981</risdate><volume>13</volume><issue>2</issue><spage>108</spage><epage>110</epage><pages>108-110</pages><issn>0020-1383</issn><eissn>1879-0267</eissn><abstract>Serum lipoprotein electrophoresis and other laboratory tests were made on 14 injured patients over 10 days. Reduction in the pre-beta fraction to an average of 6 per cent, with an elevation of the alpha lipoprotein fraction to an average of 41 per cent, were recorded. The patients without complications regained their normal lipoprotein pattern within 48 hours, while in the two cases who developed fat embolism, the deranged pattern lasted for up to 10 days.
The clinical diagnosis of fat embolism is based on signs that appear generally within 3 days following injury.
As prognosis depends on early diagnosis, in order to start treatment before full blown clinical signs are present, there is the need for a laboratory test which gives early results and is reliable and easy to perform.
This study shows an apparently distinct pattern of the serum lipoproteins which may provide us with a warning about which patients are at risk of developing fat embolism.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>7327722</pmid><doi>10.1016/0020-1383(81)90043-7</doi><tpages>3</tpages></addata></record> |
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| ispartof | Injury, 1981-09, Vol.13 (2), p.108-110 |
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| language | eng |
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| source | Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE |
| subjects | Adolescent Adult Aged Blood Protein Electrophoresis Electrophoresis, Agar Gel Embolism, Fat - blood Embolism, Fat - etiology Female Femoral Fractures - blood Fractures, Bone - blood Fractures, Closed - blood Fractures, Closed - complications Humans Lipoproteins - blood Lumbar Vertebrae - injuries Male Middle Aged Pelvic Bones - injuries Tibial Fractures - blood |
| title | Lipoprotein electrophoresis in fat embolism: a preliminary report |
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